PAX3 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PAX3

PAX3 isoform 1. (505 aa)

Predicted Functional Partners:

NCOA1

0.911

ENSPPYP00000024510

0.911

PAX7

0.901

SOX10

0.898

MYF5

0.754

MYOD1

0.729

FOXO1

0.705

MYOG

0.704

MYF6

0.698

MITF

0.688

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000024510	NCOA1	ENSPPYP00000024510	ENSPPYP00000014068	annotation not available	Nuclear receptor coactivator.	0.824
ENSPPYP00000024510	PAX3	ENSPPYP00000024510	ENSPPYP00000014772	annotation not available	PAX3 isoform 1.	0.911
ENSPPYP00000024510	PAX7	ENSPPYP00000024510	ENSPPYP00000002088	annotation not available	PAX7 isoform 2.	0.483
FOXO1	MYOD1	ENSPPYP00000006042	ENSPPYP00000003961	FOXO1 isoform 1.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.456
FOXO1	MYOG	ENSPPYP00000006042	ENSPPYP00000000374	FOXO1 isoform 1.	MYOG isoform 1.	0.456
FOXO1	PAX3	ENSPPYP00000006042	ENSPPYP00000014772	FOXO1 isoform 1.	PAX3 isoform 1.	0.705
FOXO1	PAX7	ENSPPYP00000006042	ENSPPYP00000002088	FOXO1 isoform 1.	PAX7 isoform 2.	0.704
MITF	PAX3	ENSPPYP00000015346	ENSPPYP00000014772	Melanocyte inducing transcription factor.	PAX3 isoform 1.	0.688
MITF	SOX10	ENSPPYP00000015346	ENSPPYP00000013174	Melanocyte inducing transcription factor.	SOX10 isoform 2.	0.706
MYF5	MYF6	ENSPPYP00000005474	ENSPPYP00000005473	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor 6.	0.772
MYF5	MYOD1	ENSPPYP00000005474	ENSPPYP00000003961	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.401
MYF5	MYOG	ENSPPYP00000005474	ENSPPYP00000000374	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	MYOG isoform 1.	0.668
MYF5	PAX3	ENSPPYP00000005474	ENSPPYP00000014772	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	PAX3 isoform 1.	0.754
MYF5	PAX7	ENSPPYP00000005474	ENSPPYP00000002088	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	PAX7 isoform 2.	0.779
MYF6	MYF5	ENSPPYP00000005473	ENSPPYP00000005474	Myogenic factor 6.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.772
MYF6	MYOD1	ENSPPYP00000005473	ENSPPYP00000003961	Myogenic factor 6.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.754
MYF6	MYOG	ENSPPYP00000005473	ENSPPYP00000000374	Myogenic factor 6.	MYOG isoform 1.	0.708
MYF6	PAX3	ENSPPYP00000005473	ENSPPYP00000014772	Myogenic factor 6.	PAX3 isoform 1.	0.698
MYF6	PAX7	ENSPPYP00000005473	ENSPPYP00000002088	Myogenic factor 6.	PAX7 isoform 2.	0.658
MYOD1	FOXO1	ENSPPYP00000003961	ENSPPYP00000006042	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	FOXO1 isoform 1.	0.456