INPP5D protein (Pongo abelii) - STRING interaction network

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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Score

INPP5D

INPP5D isoform 3. (1144 aa)

Predicted Functional Partners:

SHC1

0.970

LYN

0.954

PECAM1

0.912

GRB2

0.900

FCGR2B

0.840

PTPN6

0.833

SHC3

0.750

SRC

0.742

TYROBP

0.719

CD2AP

0.705

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD2AP	GRB2	ENSPPYP00000018659	ENSPPYP00000009686	CD2 associated protein.	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	0.693
CD2AP	INPP5D	ENSPPYP00000018659	ENSPPYP00000014855	CD2 associated protein.	INPP5D isoform 3.	0.705
CD2AP	SRC	ENSPPYP00000018659	ENSPPYP00000012270	CD2 associated protein.	Tyrosine-protein kinase.	0.571
FCGR2B	INPP5D	ENSPPYP00000000693	ENSPPYP00000014855	FCGR2B isoform 1.	INPP5D isoform 3.	0.840
FCGR2B	LYN	ENSPPYP00000000693	ENSPPYP00000020857	FCGR2B isoform 1.	Tyrosine-protein kinase.	0.796
FCGR2B	PECAM1	ENSPPYP00000000693	ENSPPYP00000009599	FCGR2B isoform 1.	PECAM1 isoform 1.	0.477
FCGR2B	PTPN6	ENSPPYP00000000693	ENSPPYP00000004802	FCGR2B isoform 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.647
GRB2	CD2AP	ENSPPYP00000009686	ENSPPYP00000018659	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	CD2 associated protein.	0.693
GRB2	INPP5D	ENSPPYP00000009686	ENSPPYP00000014855	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	INPP5D isoform 3.	0.900
GRB2	LYN	ENSPPYP00000009686	ENSPPYP00000020857	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	Tyrosine-protein kinase.	0.813
GRB2	PTPN6	ENSPPYP00000009686	ENSPPYP00000004802	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.930
GRB2	SHC1	ENSPPYP00000009686	ENSPPYP00000000893	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity).	0.999
GRB2	SHC3	ENSPPYP00000009686	ENSPPYP00000021691	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	SHC3 isoform 1.	0.952
GRB2	SRC	ENSPPYP00000009686	ENSPPYP00000012270	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	Tyrosine-protein kinase.	0.991
GRB2	TYROBP	ENSPPYP00000009686	ENSPPYP00000011071	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	TYRO protein tyrosine kinase binding protein.	0.483
INPP5D	CD2AP	ENSPPYP00000014855	ENSPPYP00000018659	INPP5D isoform 3.	CD2 associated protein.	0.705
INPP5D	FCGR2B	ENSPPYP00000014855	ENSPPYP00000000693	INPP5D isoform 3.	FCGR2B isoform 1.	0.840
INPP5D	GRB2	ENSPPYP00000014855	ENSPPYP00000009686	INPP5D isoform 3.	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	0.900
INPP5D	LYN	ENSPPYP00000014855	ENSPPYP00000020857	INPP5D isoform 3.	Tyrosine-protein kinase.	0.954
INPP5D	PECAM1	ENSPPYP00000014855	ENSPPYP00000009599	INPP5D isoform 3.	PECAM1 isoform 1.	0.912