| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKR1C2 | CYP1A1 | ENSPPYP00000002373 | ENSPPYP00000007536 | Aldo-keto reductase family 1 member C1 homolog; Belongs to the aldo/keto reductase family. | CYP1A1 isoform 1; Belongs to the cytochrome P450 family. | 0.909 |
| AKR1C2 | CYP2A13 | ENSPPYP00000002373 | ENSPPYP00000011203 | Aldo-keto reductase family 1 member C1 homolog; Belongs to the aldo/keto reductase family. | CYP2A13 isoform 1; Belongs to the cytochrome P450 family. | 0.905 |
| AKR1C2 | CYP2E1 | ENSPPYP00000002373 | ENSPPYP00000003264 | Aldo-keto reductase family 1 member C1 homolog; Belongs to the aldo/keto reductase family. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.937 |
| AKR1C2 | CYP3A4 | ENSPPYP00000002373 | ENSPPYP00000019486 | Aldo-keto reductase family 1 member C1 homolog; Belongs to the aldo/keto reductase family. | Cytochrome P450 family 3 subfamily A member 4. | 0.939 |
| AKR1C2 | UGT1A3 | ENSPPYP00000002373 | ENSPPYP00000014864 | Aldo-keto reductase family 1 member C1 homolog; Belongs to the aldo/keto reductase family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.929 |
| AOX1 | CR201_G0048502 | ENSPPYP00000014589 | ENSPPYP00000024366 | AOX1 isoform 2. | CYP3A7 isoform 2. | 0.923 |
| AOX1 | CYP1A1 | ENSPPYP00000014589 | ENSPPYP00000007536 | AOX1 isoform 2. | CYP1A1 isoform 1; Belongs to the cytochrome P450 family. | 0.928 |
| AOX1 | CYP3A4 | ENSPPYP00000014589 | ENSPPYP00000019486 | AOX1 isoform 2. | Cytochrome P450 family 3 subfamily A member 4. | 0.931 |
| AOX1 | SULT1E1 | ENSPPYP00000014589 | ENSPPYP00000023936 | AOX1 isoform 2. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.503 |
| AOX1 | UGT1A3 | ENSPPYP00000014589 | ENSPPYP00000014864 | AOX1 isoform 2. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.939 |
| COMT | CYP1A1 | ENSPPYP00000012926 | ENSPPYP00000007536 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | CYP1A1 isoform 1; Belongs to the cytochrome P450 family. | 0.946 |
| COMT | UGT1A3 | ENSPPYP00000012926 | ENSPPYP00000014864 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.947 |
| CR201_G0048502 | AOX1 | ENSPPYP00000024366 | ENSPPYP00000014589 | CYP3A7 isoform 2. | AOX1 isoform 2. | 0.923 |
| CR201_G0048502 | CYP1A1 | ENSPPYP00000024366 | ENSPPYP00000007536 | CYP3A7 isoform 2. | CYP1A1 isoform 1; Belongs to the cytochrome P450 family. | 0.951 |
| CR201_G0048502 | CYP2A13 | ENSPPYP00000024366 | ENSPPYP00000011203 | CYP3A7 isoform 2. | CYP2A13 isoform 1; Belongs to the cytochrome P450 family. | 0.494 |
| CR201_G0048502 | CYP2E1 | ENSPPYP00000024366 | ENSPPYP00000003264 | CYP3A7 isoform 2. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.490 |
| CR201_G0048502 | CYP3A4 | ENSPPYP00000024366 | ENSPPYP00000019486 | CYP3A7 isoform 2. | Cytochrome P450 family 3 subfamily A member 4. | 0.930 |
| CR201_G0048502 | UGT1A3 | ENSPPYP00000024366 | ENSPPYP00000014864 | CYP3A7 isoform 2. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.925 |
| CYP19A1 | CYP1A1 | ENSPPYP00000007338 | ENSPPYP00000007536 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | CYP1A1 isoform 1; Belongs to the cytochrome P450 family. | 0.944 |
| CYP19A1 | CYP2E1 | ENSPPYP00000007338 | ENSPPYP00000003264 | Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.424 |
