| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NSFL1C | PPP1CA | ENSPPYP00000012121 | ENSPPYP00000003472 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.443 |
| NSFL1C | PPP1CB | ENSPPYP00000012121 | ENSPPYP00000013994 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] | 0.435 |
| NSFL1C | PPP1CC | ENSPPYP00000012121 | ENSPPYP00000005654 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.443 |
| NSFL1C | PPP1R11 | ENSPPYP00000012121 | ENSPPYP00000023843 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | PPP1R11 isoform 1. | 0.692 |
| NSFL1C | PPP1R7 | ENSPPYP00000012121 | ENSPPYP00000014933 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | Protein phosphatase 1 regulatory subunit 7; Regulatory subunit of protein phosphatase 1. | 0.739 |
| NSFL1C | UBXN2B | ENSPPYP00000012121 | ENSPPYP00000020868 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | UBX domain protein 2B. | 0.736 |
| NSFL1C | VCP | ENSPPYP00000012121 | ENSPPYP00000021408 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | Transitional endoplasmic reticulum ATPase isoform X1. | 0.999 |
| PPP1CA | NSFL1C | ENSPPYP00000003472 | ENSPPYP00000012121 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | 0.443 |
| PPP1CA | PPP1CB | ENSPPYP00000003472 | ENSPPYP00000013994 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] | 0.999 |
| PPP1CA | PPP1CC | ENSPPYP00000003472 | ENSPPYP00000005654 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.999 |
| PPP1CA | PPP1R11 | ENSPPYP00000003472 | ENSPPYP00000023843 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | PPP1R11 isoform 1. | 0.854 |
| PPP1CA | PPP1R16B | ENSPPYP00000003472 | ENSPPYP00000012290 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | PPP1R16B isoform 1. | 0.692 |
| PPP1CA | PPP1R7 | ENSPPYP00000003472 | ENSPPYP00000014933 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Protein phosphatase 1 regulatory subunit 7; Regulatory subunit of protein phosphatase 1. | 0.883 |
| PPP1CA | PPP1R8 | ENSPPYP00000003472 | ENSPPYP00000001910 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Protein phosphatase 1 regulatory subunit 8. | 0.871 |
| PPP1CA | SH2D4A | ENSPPYP00000003472 | ENSPPYP00000020613 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | SH2D4A isoform 1. | 0.746 |
| PPP1CA | UBXN2B | ENSPPYP00000003472 | ENSPPYP00000020868 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | UBX domain protein 2B. | 0.436 |
| PPP1CA | VCP | ENSPPYP00000003472 | ENSPPYP00000021408 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Transitional endoplasmic reticulum ATPase isoform X1. | 0.457 |
| PPP1CB | NSFL1C | ENSPPYP00000013994 | ENSPPYP00000012121 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | 0.435 |
| PPP1CB | PPP1CA | ENSPPYP00000013994 | ENSPPYP00000003472 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.999 |
| PPP1CB | PPP1CC | ENSPPYP00000013994 | ENSPPYP00000005654 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.999 |
