| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKR1C4 | CR201_G0032337-2 | ENSPPYP00000002376 | ENSPPYP00000014972 | Aldo-keto reductase family 1 member C3 homolog; Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. | CYP27A1 isoform 5. | 0.922 |
| AKR1C4 | CYP8B1 | ENSPPYP00000002376 | ENSPPYP00000015629 | Aldo-keto reductase family 1 member C3 homolog; Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.918 |
| CH25H | CR201_G0032337-2 | ENSPPYP00000002851 | ENSPPYP00000014972 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | CYP27A1 isoform 5. | 0.936 |
| CH25H | CYP46A1 | ENSPPYP00000002851 | ENSPPYP00000006975 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | CYP46A1 isoform 2; Belongs to the cytochrome P450 family. | 0.952 |
| CH25H | CYP7A1 | ENSPPYP00000002851 | ENSPPYP00000020869 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.968 |
| CH25H | CYP7B1 | ENSPPYP00000002851 | ENSPPYP00000020894 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.979 |
| CH25H | CYP8B1 | ENSPPYP00000002851 | ENSPPYP00000015629 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.691 |
| CH25H | DHCR24 | ENSPPYP00000002851 | ENSPPYP00000001525 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | DHCR24 isoform 1. | 0.912 |
| CH25H | DHCR7 | ENSPPYP00000002851 | ENSPPYP00000003422 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | DHCR7 isoform 1. | 0.946 |
| CH25H | SOAT1 | ENSPPYP00000002851 | ENSPPYP00000000531 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | O-acyltransferase. | 0.845 |
| CR201_G0032337-2 | AKR1C4 | ENSPPYP00000014972 | ENSPPYP00000002376 | CYP27A1 isoform 5. | Aldo-keto reductase family 1 member C3 homolog; Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. | 0.922 |
| CR201_G0032337-2 | CH25H | ENSPPYP00000014972 | ENSPPYP00000002851 | CYP27A1 isoform 5. | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | 0.936 |
| CR201_G0032337-2 | CYP46A1 | ENSPPYP00000014972 | ENSPPYP00000006975 | CYP27A1 isoform 5. | CYP46A1 isoform 2; Belongs to the cytochrome P450 family. | 0.927 |
| CR201_G0032337-2 | CYP7A1 | ENSPPYP00000014972 | ENSPPYP00000020869 | CYP27A1 isoform 5. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.984 |
| CR201_G0032337-2 | CYP7B1 | ENSPPYP00000014972 | ENSPPYP00000020894 | CYP27A1 isoform 5. | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.969 |
| CR201_G0032337-2 | CYP8B1 | ENSPPYP00000014972 | ENSPPYP00000015629 | CYP27A1 isoform 5. | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.953 |
| CR201_G0032337-2 | DHCR24 | ENSPPYP00000014972 | ENSPPYP00000001525 | CYP27A1 isoform 5. | DHCR24 isoform 1. | 0.830 |
| CR201_G0032337-2 | DHCR7 | ENSPPYP00000014972 | ENSPPYP00000003422 | CYP27A1 isoform 5. | DHCR7 isoform 1. | 0.876 |
| CR201_G0032337-2 | SLC27A5 | ENSPPYP00000014972 | ENSPPYP00000011775 | CYP27A1 isoform 5. | Solute carrier family 27 member 5. | 0.934 |
| CR201_G0032337-2 | SOAT1 | ENSPPYP00000014972 | ENSPPYP00000000531 | CYP27A1 isoform 5. | O-acyltransferase. | 0.834 |
