STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXND1PLXND1 isoform 1. (1818 aa)    
Predicted Functional Partners:
SEMA3E
SEMA3E isoform 1; Belongs to the semaphorin family.
    
 0.996
SEMA4A
SEMA4A isoform 10; Belongs to the semaphorin family.
    
 0.972
SEMA3C
Semaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
    
 0.869
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.845
SEMA3A
SEMA3A isoform 1; Belongs to the semaphorin family.
    
 0.822
SEMA4D
SEMA4D isoform 10; Belongs to the semaphorin family.
    
 0.798
GIPC1
GIPC PDZ domain containing family member 1.
    
 
 0.736
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 
 0.728
SEMA6A
SEMA6A isoform 1; Belongs to the semaphorin family.
    
 0.727
SEMA7A
SEMA7A isoform 1; Belongs to the semaphorin family.
    
 0.716
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.