| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCZ1 | CHM | ENSPPYP00000019450 | ENSPPYP00000022968 | CCZ1B isoform 5. | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | 0.606 |
| CCZ1 | MON1A | ENSPPYP00000019450 | ENSPPYP00000015505 | CCZ1B isoform 5. | Vacuolar fusion protein MON1 homolog A. | 0.993 |
| CCZ1 | MON1B | ENSPPYP00000019450 | ENSPPYP00000008544 | CCZ1B isoform 5. | MON1B isoform 2. | 0.989 |
| CCZ1 | RAB7A | ENSPPYP00000019450 | ENSPPYP00000015022 | CCZ1B isoform 5. | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] | 0.988 |
| CCZ1 | TBC1D15 | ENSPPYP00000019450 | ENSPPYP00000005441 | CCZ1B isoform 5. | TBC1D15 isoform 2. | 0.490 |
| CCZ1 | VPS11 | ENSPPYP00000019450 | ENSPPYP00000004530 | CCZ1B isoform 5. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.872 |
| CHM | CCZ1 | ENSPPYP00000022968 | ENSPPYP00000019450 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | CCZ1B isoform 5. | 0.606 |
| CHM | MON1A | ENSPPYP00000022968 | ENSPPYP00000015505 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Vacuolar fusion protein MON1 homolog A. | 0.420 |
| CHM | MON1B | ENSPPYP00000022968 | ENSPPYP00000008544 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | MON1B isoform 2. | 0.420 |
| CHM | RAB2A | ENSPPYP00000022968 | ENSPPYP00000020877 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Ras-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex. | 0.598 |
| CHM | RAB7A | ENSPPYP00000022968 | ENSPPYP00000015022 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] | 0.975 |
| MON1A | CCZ1 | ENSPPYP00000015505 | ENSPPYP00000019450 | Vacuolar fusion protein MON1 homolog A. | CCZ1B isoform 5. | 0.993 |
| MON1A | CHM | ENSPPYP00000015505 | ENSPPYP00000022968 | Vacuolar fusion protein MON1 homolog A. | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | 0.420 |
| MON1A | MON1B | ENSPPYP00000015505 | ENSPPYP00000008544 | Vacuolar fusion protein MON1 homolog A. | MON1B isoform 2. | 0.926 |
| MON1A | RAB7A | ENSPPYP00000015505 | ENSPPYP00000015022 | Vacuolar fusion protein MON1 homolog A. | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] | 0.986 |
| MON1A | TBC1D15 | ENSPPYP00000015505 | ENSPPYP00000005441 | Vacuolar fusion protein MON1 homolog A. | TBC1D15 isoform 2. | 0.642 |
| MON1A | VPS11 | ENSPPYP00000015505 | ENSPPYP00000004530 | Vacuolar fusion protein MON1 homolog A. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.738 |
| MON1B | CCZ1 | ENSPPYP00000008544 | ENSPPYP00000019450 | MON1B isoform 2. | CCZ1B isoform 5. | 0.989 |
| MON1B | CHM | ENSPPYP00000008544 | ENSPPYP00000022968 | MON1B isoform 2. | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | 0.420 |
| MON1B | MON1A | ENSPPYP00000008544 | ENSPPYP00000015505 | MON1B isoform 2. | Vacuolar fusion protein MON1 homolog A. | 0.926 |
