| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGXT2 | F13B | ENSPPYP00000017192 | ENSPPYP00000024425 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | F13B isoform 1. | 0.587 |
| AGXT2 | HGD | ENSPPYP00000017192 | ENSPPYP00000015100 | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Homogentisate 1,2-dioxygenase; Belongs to the homogentisate dioxygenase family. | 0.699 |
| ENSPPYP00000023821 | F13B | ENSPPYP00000023821 | ENSPPYP00000024425 | annotation not available | F13B isoform 1. | 0.587 |
| ENSPPYP00000023821 | HGD | ENSPPYP00000023821 | ENSPPYP00000015100 | annotation not available | Homogentisate 1,2-dioxygenase; Belongs to the homogentisate dioxygenase family. | 0.699 |
| F13B | AGXT2 | ENSPPYP00000024425 | ENSPPYP00000017192 | F13B isoform 1. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.587 |
| F13B | ENSPPYP00000023821 | ENSPPYP00000024425 | ENSPPYP00000023821 | F13B isoform 1. | annotation not available | 0.587 |
| F13B | HGD | ENSPPYP00000024425 | ENSPPYP00000015100 | F13B isoform 1. | Homogentisate 1,2-dioxygenase; Belongs to the homogentisate dioxygenase family. | 0.853 |
| F13B | PAH | ENSPPYP00000024425 | ENSPPYP00000005573 | F13B isoform 1. | Phenylalanine hydroxylase. | 0.421 |
| FAH | GSTZ1 | ENSPPYP00000007618 | ENSPPYP00000006849 | Fumarylacetoacetase. | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. | 0.995 |
| FAH | HGD | ENSPPYP00000007618 | ENSPPYP00000015100 | Fumarylacetoacetase. | Homogentisate 1,2-dioxygenase; Belongs to the homogentisate dioxygenase family. | 0.887 |
| FAH | HPD | ENSPPYP00000007618 | ENSPPYP00000005761 | Fumarylacetoacetase. | 4-hydroxyphenylpyruvate dioxygenase. | 0.879 |
| FAH | HPDL | ENSPPYP00000007618 | ENSPPYP00000001642 | Fumarylacetoacetase. | 4-hydroxyphenylpyruvate dioxygenase. | 0.723 |
| FAH | HPS4 | ENSPPYP00000007618 | ENSPPYP00000024247 | Fumarylacetoacetase. | HPS4 isoform 6. | 0.442 |
| FAH | PAH | ENSPPYP00000007618 | ENSPPYP00000005573 | Fumarylacetoacetase. | Phenylalanine hydroxylase. | 0.497 |
| FAH | TAT | ENSPPYP00000007618 | ENSPPYP00000008501 | Fumarylacetoacetase. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.660 |
| GSTZ1 | FAH | ENSPPYP00000006849 | ENSPPYP00000007618 | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. | Fumarylacetoacetase. | 0.995 |
| GSTZ1 | HGD | ENSPPYP00000006849 | ENSPPYP00000015100 | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. | Homogentisate 1,2-dioxygenase; Belongs to the homogentisate dioxygenase family. | 0.995 |
| GSTZ1 | HPD | ENSPPYP00000006849 | ENSPPYP00000005761 | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. | 4-hydroxyphenylpyruvate dioxygenase. | 0.553 |
| GSTZ1 | HPDL | ENSPPYP00000006849 | ENSPPYP00000001642 | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. | 4-hydroxyphenylpyruvate dioxygenase. | 0.619 |
| HGD | AGXT2 | ENSPPYP00000015100 | ENSPPYP00000017192 | Homogentisate 1,2-dioxygenase; Belongs to the homogentisate dioxygenase family. | Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.699 |
