STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAP43Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). (238 aa)    
Predicted Functional Partners:
CALML5
Calmodulin like 5.
   
 
 0.869
CALML3
CALML3 isoform 1; Belongs to the calmodulin family.
   
 
 0.869
CALML6
Calmodulin like 6.
   
 
 0.866
CALML4
LOW QUALITY PROTEIN: calmodulin-like protein 4.
   
 
 0.866
CNTN2
CNTN2 isoform 10.
   
  
 0.727
SYN1
SYN1 isoform 2.
   
  
 0.704
SYP
SYP isoform 1.
   
  
 0.695
NGF
NGF isoform 1; Belongs to the NGF-beta family.
      
 0.684
BASP1
Brain abundant membrane attached signal protein 1.
      
 0.682
CALM1
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).
   
 
 0.668
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (26%) [HD]