| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH1L2 | AMT | ENSPPYP00000005589 | ENSPPYP00000015519 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.921 |
| ALDH1L2 | DHFR2 | ENSPPYP00000005589 | ENSPPYP00000015237 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | 0.962 |
| ALDH1L2 | DMGDH | ENSPPYP00000005589 | ENSPPYP00000017421 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | DMGDH isoform 5. | 0.913 |
| ALDH1L2 | GART | ENSPPYP00000005589 | ENSPPYP00000012701 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.952 |
| ALDH1L2 | MTHFD1 | ENSPPYP00000005589 | ENSPPYP00000006705 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.951 |
| ALDH1L2 | SARDH | ENSPPYP00000005589 | ENSPPYP00000022141 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | SARDH isoform 2. | 0.939 |
| ALDH1L2 | SHMT1 | ENSPPYP00000005589 | ENSPPYP00000009057 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. | 0.970 |
| ALDH1L2 | SHMT2 | ENSPPYP00000005589 | ENSPPYP00000005336 | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.944 |
| AMT | ALDH1L2 | ENSPPYP00000015519 | ENSPPYP00000005589 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.921 |
| AMT | DHFR2 | ENSPPYP00000015519 | ENSPPYP00000015237 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | 0.954 |
| AMT | DMGDH | ENSPPYP00000015519 | ENSPPYP00000017421 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | DMGDH isoform 5. | 0.908 |
| AMT | FPGS | ENSPPYP00000015519 | ENSPPYP00000022000 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.586 |
| AMT | GART | ENSPPYP00000015519 | ENSPPYP00000012701 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.972 |
| AMT | MTHFD1 | ENSPPYP00000015519 | ENSPPYP00000006705 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.950 |
| AMT | SARDH | ENSPPYP00000015519 | ENSPPYP00000022141 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | SARDH isoform 2. | 0.908 |
| AMT | SHMT1 | ENSPPYP00000015519 | ENSPPYP00000009057 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. | 0.974 |
| AMT | SHMT2 | ENSPPYP00000015519 | ENSPPYP00000005336 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.974 |
| AMT | TYMS | ENSPPYP00000015519 | ENSPPYP00000010155 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Thymidylate synthetase. | 0.960 |
| DHFR2 | ALDH1L2 | ENSPPYP00000015237 | ENSPPYP00000005589 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | 10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. | 0.962 |
| DHFR2 | AMT | ENSPPYP00000015237 | ENSPPYP00000015519 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.954 |
