| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MIOS | SEC13 | ENSPPYP00000019940 | ENSPPYP00000015269 | GATOR complex protein MIOS; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. | 0.999 |
| MIOS | SEH1L | ENSPPYP00000019940 | ENSPPYP00000010077 | GATOR complex protein MIOS; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. | Nucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Belongs to the WD repeat SEC13 family. | 0.999 |
| MIOS | WDR24 | ENSPPYP00000019940 | ENSPPYP00000007839 | GATOR complex protein MIOS; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. | WDR24 isoform 1. | 0.999 |
| MIOS | WDR59 | ENSPPYP00000019940 | ENSPPYP00000008526 | GATOR complex protein MIOS; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. | WDR59 isoform 2. | 0.999 |
| NUP107 | NUP133 | ENSPPYP00000005413 | ENSPPYP00000000128 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | NUP133 isoform 1. | 0.999 |
| NUP107 | NUP37 | ENSPPYP00000005413 | ENSPPYP00000005569 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | NUP37 isoform 1. | 0.999 |
| NUP107 | NUP85 | ENSPPYP00000005413 | ENSPPYP00000009681 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). | 0.999 |
| NUP107 | SEC13 | ENSPPYP00000005413 | ENSPPYP00000015269 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. | 0.999 |
| NUP107 | SEH1L | ENSPPYP00000005413 | ENSPPYP00000010077 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | Nucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Belongs to the WD repeat SEC13 family. | 0.998 |
| NUP107 | WDR24 | ENSPPYP00000005413 | ENSPPYP00000007839 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | WDR24 isoform 1. | 0.492 |
| NUP133 | NUP107 | ENSPPYP00000000128 | ENSPPYP00000005413 | NUP133 isoform 1. | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | 0.999 |
| NUP133 | NUP37 | ENSPPYP00000000128 | ENSPPYP00000005569 | NUP133 isoform 1. | NUP37 isoform 1. | 0.998 |
| NUP133 | NUP85 | ENSPPYP00000000128 | ENSPPYP00000009681 | NUP133 isoform 1. | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). | 0.999 |
| NUP133 | SEC13 | ENSPPYP00000000128 | ENSPPYP00000015269 | NUP133 isoform 1. | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. | 0.998 |
| NUP133 | SEH1L | ENSPPYP00000000128 | ENSPPYP00000010077 | NUP133 isoform 1. | Nucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Belongs to the WD repeat SEC13 family. | 0.998 |
| NUP133 | WDR59 | ENSPPYP00000000128 | ENSPPYP00000008526 | NUP133 isoform 1. | WDR59 isoform 2. | 0.481 |
| NUP37 | NUP107 | ENSPPYP00000005569 | ENSPPYP00000005413 | NUP37 isoform 1. | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). | 0.999 |
| NUP37 | NUP133 | ENSPPYP00000005569 | ENSPPYP00000000128 | NUP37 isoform 1. | NUP133 isoform 1. | 0.998 |
| NUP37 | NUP85 | ENSPPYP00000005569 | ENSPPYP00000009681 | NUP37 isoform 1. | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). | 0.999 |
| NUP37 | SEC13 | ENSPPYP00000005569 | ENSPPYP00000015269 | NUP37 isoform 1. | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. | 0.998 |
