| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABI1 | ARPC2 | ENSPPYP00000002516 | ENSPPYP00000014708 | Abl interactor 1. | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | 0.960 |
| ABI1 | ARPC3 | ENSPPYP00000002516 | ENSPPYP00000005645 | Abl interactor 1. | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. | 0.930 |
| ABI1 | BRK1 | ENSPPYP00000002516 | ENSPPYP00000015277 | Abl interactor 1. | BRK1 isoform 1. | 0.994 |
| ABI1 | CR201_G0042601 | ENSPPYP00000002516 | ENSPPYP00000001919 | Abl interactor 1. | WASF2 isoform 2. | 0.968 |
| ABI1 | CYFIP1 | ENSPPYP00000002516 | ENSPPYP00000007096 | Abl interactor 1. | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.996 |
| ABI1 | CYFIP2 | ENSPPYP00000002516 | ENSPPYP00000017891 | Abl interactor 1. | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | 0.998 |
| ABI1 | NCKAP1 | ENSPPYP00000002516 | ENSPPYP00000014519 | Abl interactor 1. | NCK associated protein 1. | 0.996 |
| ABI1 | NCKAP1L | ENSPPYP00000002516 | ENSPPYP00000005254 | Abl interactor 1. | NCK associated protein 1 like. | 0.987 |
| ABI1 | WASF1 | ENSPPYP00000002516 | ENSPPYP00000018938 | Abl interactor 1. | Wiskott-Aldrich syndrome protein family member 1; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity); Belongs to the SCAR/WAVE family. | 0.989 |
| ABI1 | WASF3 | ENSPPYP00000002516 | ENSPPYP00000005957 | Abl interactor 1. | WASP family member 3. | 0.990 |
| ARPC2 | ABI1 | ENSPPYP00000014708 | ENSPPYP00000002516 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | Abl interactor 1. | 0.960 |
| ARPC2 | ARPC3 | ENSPPYP00000014708 | ENSPPYP00000005645 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. | 0.999 |
| ARPC2 | BRK1 | ENSPPYP00000014708 | ENSPPYP00000015277 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | BRK1 isoform 1. | 0.984 |
| ARPC2 | CR201_G0042601 | ENSPPYP00000014708 | ENSPPYP00000001919 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | WASF2 isoform 2. | 0.695 |
| ARPC2 | CYFIP1 | ENSPPYP00000014708 | ENSPPYP00000007096 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.939 |
| ARPC2 | CYFIP2 | ENSPPYP00000014708 | ENSPPYP00000017891 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | 0.959 |
| ARPC2 | NCKAP1 | ENSPPYP00000014708 | ENSPPYP00000014519 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | NCK associated protein 1. | 0.905 |
| ARPC2 | NCKAP1L | ENSPPYP00000014708 | ENSPPYP00000005254 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | NCK associated protein 1 like. | 0.908 |
| ARPC2 | WASF1 | ENSPPYP00000014708 | ENSPPYP00000018938 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | Wiskott-Aldrich syndrome protein family member 1; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity); Belongs to the SCAR/WAVE family. | 0.985 |
| ARPC2 | WASF3 | ENSPPYP00000014708 | ENSPPYP00000005957 | Actin-related protein 2/3 complex subunit 2; Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promot [...] | WASP family member 3. | 0.946 |
