Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITPR1ITPR1 isoform 3. (2769 aa)    
Predicted Functional Partners:
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
  
0.996
MRVI1
MRVI1 isoform 6.
    
 0.996
ITPR3
ITPR3 isoform 1.
  
0.991
HTT
HTT isoform 1.
    
 0.979
PRKACG
Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.
    
 0.965
PRKACB
PRKACB isoform 9; Belongs to the protein kinase superfamily.
    
 0.963
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.960
CALML5
Calmodulin like 5.
    
 0.951
CALML3
CALML3 isoform 1; Belongs to the calmodulin family.
    
 0.951
CALML4
LOW QUALITY PROTEIN: calmodulin-like protein 4.
    
 0.947
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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