| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATXN7 | KAT2B | ENSPPYP00000015372 | ENSPPYP00000015742 | ATXN7 isoform 1. | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | 0.984 |
| ATXN7 | SGF29 | ENSPPYP00000015372 | ENSPPYP00000008178 | ATXN7 isoform 1. | SAGA complex associated factor 29. | 0.956 |
| ATXN7 | SUPT20H | ENSPPYP00000015372 | ENSPPYP00000006026 | ATXN7 isoform 1. | Transcription factor SPT20 homolog; Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy (By similarity). Belongs to the SPT20 family. | 0.968 |
| ATXN7 | TADA2B | ENSPPYP00000015372 | ENSPPYP00000016284 | ATXN7 isoform 1. | Transcriptional adapter 2-beta; Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2. | 0.972 |
| ATXN7 | TADA3 | ENSPPYP00000015372 | ENSPPYP00000015293 | ATXN7 isoform 1. | Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity). | 0.978 |
| ATXN7 | TAF10 | ENSPPYP00000015372 | ENSPPYP00000004055 | ATXN7 isoform 1. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.988 |
| ATXN7 | TAF12 | ENSPPYP00000015372 | ENSPPYP00000001889 | ATXN7 isoform 1. | TAF12 isoform 2. | 0.969 |
| ATXN7 | TAF9B | ENSPPYP00000015372 | ENSPPYP00000022945 | ATXN7 isoform 1. | Transcription initiation factor TFIID subunit 9B; Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity). | 0.954 |
| ATXN7 | TRRAP | ENSPPYP00000015372 | ENSPPYP00000019457 | ATXN7 isoform 1. | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.987 |
| ATXN7 | USP22 | ENSPPYP00000015372 | ENSPPYP00000009076 | ATXN7 isoform 1. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.978 |
| KAT2B | ATXN7 | ENSPPYP00000015742 | ENSPPYP00000015372 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | ATXN7 isoform 1. | 0.984 |
| KAT2B | SGF29 | ENSPPYP00000015742 | ENSPPYP00000008178 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | SAGA complex associated factor 29. | 0.995 |
| KAT2B | SUPT20H | ENSPPYP00000015742 | ENSPPYP00000006026 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Transcription factor SPT20 homolog; Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail. Required for starvation-induced ATG9A trafficking during autophagy (By similarity). Belongs to the SPT20 family. | 0.971 |
| KAT2B | TADA2B | ENSPPYP00000015742 | ENSPPYP00000016284 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Transcriptional adapter 2-beta; Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2. | 0.994 |
| KAT2B | TADA3 | ENSPPYP00000015742 | ENSPPYP00000015293 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity). | 0.998 |
| KAT2B | TAF10 | ENSPPYP00000015742 | ENSPPYP00000004055 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.997 |
| KAT2B | TAF12 | ENSPPYP00000015742 | ENSPPYP00000001889 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | TAF12 isoform 2. | 0.980 |
| KAT2B | TAF9B | ENSPPYP00000015742 | ENSPPYP00000022945 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Transcription initiation factor TFIID subunit 9B; Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity). | 0.987 |
| KAT2B | TRRAP | ENSPPYP00000015742 | ENSPPYP00000019457 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.997 |
| KAT2B | USP22 | ENSPPYP00000015742 | ENSPPYP00000009076 | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.926 |
