DCP1A protein (Pongo abelii) - STRING interaction network

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second shell of interactors

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Predicted Interactions

gene neighborhood

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Score

DCP1A

DCP1A isoform 1. (582 aa)

Predicted Functional Partners:

ENSPPYP00000017543

0.999

DCP1B

0.998

EDC4

0.998

DDX6

0.997

EDC3

0.997

PATL1

0.996

XRN1

0.993

PNRC2

0.985

UPF1

0.956

DCP2

0.947

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCP1A	DCP1B	ENSPPYP00000015428	ENSPPYP00000004723	DCP1A isoform 1.	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	0.998
DCP1A	DCP2	ENSPPYP00000015428	ENSPPYP00000018067	DCP1A isoform 1.	m7GpppN-mRNA hydrolase; Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication- dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety. The presence of a N(6)-methyladenosine methylation at the second transcr [...]	0.947
DCP1A	DDX6	ENSPPYP00000015428	ENSPPYP00000004516	DCP1A isoform 1.	Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, may play a role in mRNA decapping.	0.997
DCP1A	EDC3	ENSPPYP00000015428	ENSPPYP00000007534	DCP1A isoform 1.	Enhancer of mRNA-decapping protein 3; Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity); Belongs to the EDC3 family.	0.997
DCP1A	EDC4	ENSPPYP00000015428	ENSPPYP00000008440	DCP1A isoform 1.	Enhancer of mRNA decapping 4.	0.998
DCP1A	ENSPPYP00000017543	ENSPPYP00000015428	ENSPPYP00000017543	DCP1A isoform 1.	annotation not available	0.999
DCP1A	PATL1	ENSPPYP00000015428	ENSPPYP00000003720	DCP1A isoform 1.	Protein PAT1 homolog 1; RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly (By similarity); Belongs to the PAT1 family.	0.996
DCP1A	PNRC2	ENSPPYP00000015428	ENSPPYP00000001999	DCP1A isoform 1.	Proline rich nuclear receptor coactivator 2.	0.985
DCP1A	UPF1	ENSPPYP00000015428	ENSPPYP00000010923	DCP1A isoform 1.	UPF1 isoform 2.	0.956
DCP1A	XRN1	ENSPPYP00000015428	ENSPPYP00000015851	DCP1A isoform 1.	5'-3' exoribonuclease 1.	0.993
DCP1B	DCP1A	ENSPPYP00000004723	ENSPPYP00000015428	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	DCP1A isoform 1.	0.998
DCP1B	DCP2	ENSPPYP00000004723	ENSPPYP00000018067	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	m7GpppN-mRNA hydrolase; Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication- dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety. The presence of a N(6)-methyladenosine methylation at the second transcr [...]	0.842
DCP1B	DDX6	ENSPPYP00000004723	ENSPPYP00000004516	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, may play a role in mRNA decapping.	0.992
DCP1B	EDC3	ENSPPYP00000004723	ENSPPYP00000007534	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	Enhancer of mRNA-decapping protein 3; Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity); Belongs to the EDC3 family.	0.993
DCP1B	EDC4	ENSPPYP00000004723	ENSPPYP00000008440	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	Enhancer of mRNA decapping 4.	0.983
DCP1B	ENSPPYP00000017543	ENSPPYP00000004723	ENSPPYP00000017543	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	annotation not available	0.993
DCP1B	PATL1	ENSPPYP00000004723	ENSPPYP00000003720	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	Protein PAT1 homolog 1; RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly (By similarity); Belongs to the PAT1 family.	0.757
DCP1B	PNRC2	ENSPPYP00000004723	ENSPPYP00000001999	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	Proline rich nuclear receptor coactivator 2.	0.760
DCP1B	UPF1	ENSPPYP00000004723	ENSPPYP00000010923	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	UPF1 isoform 2.	0.811
DCP1B	XRN1	ENSPPYP00000004723	ENSPPYP00000015851	mRNA-decapping enzyme 1B; May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7- methyl guanine cap structure from mRNA molecules, yielding a 5'- phosphorylated mRNA fragment and 7m-GDP (By similarity).	5'-3' exoribonuclease 1.	0.953