DNAH1 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

DNAH1

DNAH1 isoform 1. (4329 aa)

Predicted Functional Partners:

CMTM6

0.863

INVS

0.828

DNAH14

0.795

CD151

0.737

DNAI2

0.719

NME8

0.705

DNAI1

0.677

WDR78

0.656

SOD1

0.650

CCDC65

0.638

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC65	DNAH1	ENSPPYP00000005103	ENSPPYP00000015453	CCDC65 isoform 2.	DNAH1 isoform 1.	0.638
CCDC65	DNAH14	ENSPPYP00000005103	ENSPPYP00000000180	CCDC65 isoform 2.	DNAH14 isoform 12.	0.463
CCDC65	DNAI1	ENSPPYP00000005103	ENSPPYP00000021425	CCDC65 isoform 2.	DNAI1 isoform 1.	0.744
CCDC65	DNAI2	ENSPPYP00000005103	ENSPPYP00000009650	CCDC65 isoform 2.	DNAI2 isoform 3.	0.701
CCDC65	NME8	ENSPPYP00000005103	ENSPPYP00000019759	CCDC65 isoform 2.	NME8 isoform 1.	0.627
CCDC65	WDR78	ENSPPYP00000005103	ENSPPYP00000001470	CCDC65 isoform 2.	WDR78 isoform 1.	0.470
CD151	CMTM6	ENSPPYP00000003360	ENSPPYP00000015709	Tetraspanin.	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	0.794
CD151	DNAH1	ENSPPYP00000003360	ENSPPYP00000015453	Tetraspanin.	DNAH1 isoform 1.	0.737
CD151	INVS	ENSPPYP00000003360	ENSPPYP00000021789	Tetraspanin.	INVS isoform 2.	0.691
CMTM6	CD151	ENSPPYP00000015709	ENSPPYP00000003360	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	Tetraspanin.	0.794
CMTM6	DNAH1	ENSPPYP00000015709	ENSPPYP00000015453	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	DNAH1 isoform 1.	0.863
CMTM6	INVS	ENSPPYP00000015709	ENSPPYP00000021789	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	INVS isoform 2.	0.862
DNAH1	CCDC65	ENSPPYP00000015453	ENSPPYP00000005103	DNAH1 isoform 1.	CCDC65 isoform 2.	0.638
DNAH1	CD151	ENSPPYP00000015453	ENSPPYP00000003360	DNAH1 isoform 1.	Tetraspanin.	0.737
DNAH1	CMTM6	ENSPPYP00000015453	ENSPPYP00000015709	DNAH1 isoform 1.	CKLF-like MARVEL transmembrane domain-containing protein 6; Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately trigge [...]	0.863
DNAH1	DNAH14	ENSPPYP00000015453	ENSPPYP00000000180	DNAH1 isoform 1.	DNAH14 isoform 12.	0.795
DNAH1	DNAI1	ENSPPYP00000015453	ENSPPYP00000021425	DNAH1 isoform 1.	DNAI1 isoform 1.	0.677
DNAH1	DNAI2	ENSPPYP00000015453	ENSPPYP00000009650	DNAH1 isoform 1.	DNAI2 isoform 3.	0.719
DNAH1	INVS	ENSPPYP00000015453	ENSPPYP00000021789	DNAH1 isoform 1.	INVS isoform 2.	0.828
DNAH1	NME8	ENSPPYP00000015453	ENSPPYP00000019759	DNAH1 isoform 1.	NME8 isoform 1.	0.705