STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP3Poly [ADP-ribose] polymerase. (531 aa)    
Predicted Functional Partners:
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
  
 
0.931
CASP9
CASP9 isoform 2; Belongs to the peptidase C14A family.
    
 0.922
CASP7
CASP7 isoform 4; Belongs to the peptidase C14A family.
    
 0.922
PARP2
Poly [ADP-ribose] polymerase.
  
 
0.922
CASP3
CASP3 isoform 1; Belongs to the peptidase C14A family.
    
 0.922
GZMB
GZMB isoform 1; Belongs to the peptidase S1 family.
   
 
  0.903
PARG
Poly(ADP-ribose) glycohydrolase.
    
 0.808
APLF
Aprataxin and PNKP like factor.
    
 
 0.765
HPF1
Histone PARylation factor 1.
    
 
 0.673
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
 0.630
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.