RASSF1 protein (Pongo abelii) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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Score

RASSF1

RASSF1 isoform 4. (304 aa)

Predicted Functional Partners:

STK4

0.995

STK3

0.991

HRAS

0.986

NRAS

0.953

MAP1S

0.933

CCND1

0.931

RRAS

0.912

MRAS

0.912

RRAS2

0.912

CR201_G0022133

0.906

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCND1	HRAS	ENSPPYP00000003434	ENSPPYP00000003333	G1/S-specific cyclin-D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...]	HRas proto-oncogene, GTPase.	0.571
CCND1	NRAS	ENSPPYP00000003434	ENSPPYP00000001163	G1/S-specific cyclin-D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...]	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.599
CCND1	RASSF1	ENSPPYP00000003434	ENSPPYP00000015490	G1/S-specific cyclin-D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...]	RASSF1 isoform 4.	0.931
CR201_G0022133	HRAS	ENSPPYP00000000306	ENSPPYP00000003333	RASSF5 isoform 7.	HRas proto-oncogene, GTPase.	0.962
CR201_G0022133	MAP1S	ENSPPYP00000000306	ENSPPYP00000010893	RASSF5 isoform 7.	MAP1S isoform 1.	0.433
CR201_G0022133	MRAS	ENSPPYP00000000306	ENSPPYP00000015821	RASSF5 isoform 7.	Muscle RAS oncogene homolog.	0.487
CR201_G0022133	NRAS	ENSPPYP00000000306	ENSPPYP00000001163	RASSF5 isoform 7.	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.654
CR201_G0022133	RASSF1	ENSPPYP00000000306	ENSPPYP00000015490	RASSF5 isoform 7.	RASSF1 isoform 4.	0.906
CR201_G0022133	RRAS	ENSPPYP00000000306	ENSPPYP00000011483	RASSF5 isoform 7.	RRAS isoform 1.	0.541
CR201_G0022133	STK3	ENSPPYP00000000306	ENSPPYP00000021064	RASSF5 isoform 7.	STK3 isoform 3.	0.899
CR201_G0022133	STK4	ENSPPYP00000000306	ENSPPYP00000012335	RASSF5 isoform 7.	STK4 isoform 1.	0.954
HRAS	CCND1	ENSPPYP00000003333	ENSPPYP00000003434	HRas proto-oncogene, GTPase.	G1/S-specific cyclin-D1; Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...]	0.571
HRAS	CR201_G0022133	ENSPPYP00000003333	ENSPPYP00000000306	HRas proto-oncogene, GTPase.	RASSF5 isoform 7.	0.962
HRAS	NRAS	ENSPPYP00000003333	ENSPPYP00000001163	HRas proto-oncogene, GTPase.	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.920
HRAS	RASSF1	ENSPPYP00000003333	ENSPPYP00000015490	HRas proto-oncogene, GTPase.	RASSF1 isoform 4.	0.986
HRAS	RRAS	ENSPPYP00000003333	ENSPPYP00000011483	HRas proto-oncogene, GTPase.	RRAS isoform 1.	0.917
MAP1S	CR201_G0022133	ENSPPYP00000010893	ENSPPYP00000000306	MAP1S isoform 1.	RASSF5 isoform 7.	0.433
MAP1S	RASSF1	ENSPPYP00000010893	ENSPPYP00000015490	MAP1S isoform 1.	RASSF1 isoform 4.	0.933
MAP1S	STK3	ENSPPYP00000010893	ENSPPYP00000021064	MAP1S isoform 1.	STK3 isoform 3.	0.424
MAP1S	STK4	ENSPPYP00000010893	ENSPPYP00000012335	MAP1S isoform 1.	STK4 isoform 1.	0.519