GNAI2 protein (Pongo abelii) - STRING interaction network

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Score

GNAI2

GNAI2 isoform 1. (303 aa)

Predicted Functional Partners:

GNAI3

0.997

GNAI1

0.975

CHRM4

0.975

P2RY12

0.974

GNB1

0.970

ADCY3

0.969

ADCY1

0.969

ADCY8

0.969

RXFP4

0.966

GPSM1

0.966

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY3	ENSPPYP00000019703	ENSPPYP00000014065	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.952
ADCY1	ADCY8	ENSPPYP00000019703	ENSPPYP00000021189	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.975
ADCY1	GNAI1	ENSPPYP00000019703	ENSPPYP00000020020	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.765
ADCY1	GNAI2	ENSPPYP00000019703	ENSPPYP00000015499	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAI2 isoform 1.	0.969
ADCY1	GNAI3	ENSPPYP00000019703	ENSPPYP00000001241	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.969
ADCY1	GNB1	ENSPPYP00000019703	ENSPPYP00000002307	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.811
ADCY3	ADCY1	ENSPPYP00000014065	ENSPPYP00000019703	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.952
ADCY3	ADCY8	ENSPPYP00000014065	ENSPPYP00000021189	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.965
ADCY3	GNAI1	ENSPPYP00000014065	ENSPPYP00000020020	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.729
ADCY3	GNAI2	ENSPPYP00000014065	ENSPPYP00000015499	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAI2 isoform 1.	0.969
ADCY3	GNAI3	ENSPPYP00000014065	ENSPPYP00000001241	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.959
ADCY3	GNB1	ENSPPYP00000014065	ENSPPYP00000002307	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.936
ADCY8	ADCY1	ENSPPYP00000021189	ENSPPYP00000019703	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.975
ADCY8	ADCY3	ENSPPYP00000021189	ENSPPYP00000014065	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.965
ADCY8	GNAI1	ENSPPYP00000021189	ENSPPYP00000020020	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.760
ADCY8	GNAI2	ENSPPYP00000021189	ENSPPYP00000015499	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAI2 isoform 1.	0.969
ADCY8	GNAI3	ENSPPYP00000021189	ENSPPYP00000001241	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.964
ADCY8	GNB1	ENSPPYP00000021189	ENSPPYP00000002307	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.794
CHRM4	GNAI1	ENSPPYP00000024135	ENSPPYP00000020020	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein G(i) subunit alpha-1.	0.430
CHRM4	GNAI2	ENSPPYP00000024135	ENSPPYP00000015499	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	GNAI2 isoform 1.	0.975