| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AK9 | CTPS1 | ENSPPYP00000018934 | ENSPPYP00000001712 | AK9 isoform 2. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.939 |
| AK9 | CTPS2 | ENSPPYP00000018934 | ENSPPYP00000022544 | AK9 isoform 2. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.939 |
| AK9 | DTYMK | ENSPPYP00000018934 | ENSPPYP00000014942 | AK9 isoform 2. | DTYMK isoform 1. | 0.949 |
| AK9 | HDDC3 | ENSPPYP00000018934 | ENSPPYP00000007700 | AK9 isoform 2. | HD domain containing 3. | 0.937 |
| AK9 | ITPA | ENSPPYP00000018934 | ENSPPYP00000012088 | AK9 isoform 2. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.930 |
| AK9 | NME4 | ENSPPYP00000018934 | ENSPPYP00000007822 | AK9 isoform 2. | Nucleoside diphosphate kinase. | 0.944 |
| AK9 | NME6 | ENSPPYP00000018934 | ENSPPYP00000015557 | AK9 isoform 2. | Nucleoside diphosphate kinase. | 0.944 |
| AK9 | NTPCR | ENSPPYP00000018934 | ENSPPYP00000000108 | AK9 isoform 2. | Nucleoside-triphosphatase, cancer-related. | 0.914 |
| AK9 | RRM1 | ENSPPYP00000018934 | ENSPPYP00000004146 | AK9 isoform 2. | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.989 |
| AK9 | RRM2 | ENSPPYP00000018934 | ENSPPYP00000014130 | AK9 isoform 2. | Ribonucleotide reductase regulatory subunit M2. | 0.983 |
| CTPS1 | AK9 | ENSPPYP00000001712 | ENSPPYP00000018934 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | AK9 isoform 2. | 0.939 |
| CTPS1 | CTPS2 | ENSPPYP00000001712 | ENSPPYP00000022544 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.991 |
| CTPS1 | ITPA | ENSPPYP00000001712 | ENSPPYP00000012088 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.638 |
| CTPS1 | NME4 | ENSPPYP00000001712 | ENSPPYP00000007822 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase. | 0.946 |
| CTPS1 | NME6 | ENSPPYP00000001712 | ENSPPYP00000015557 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase. | 0.950 |
| CTPS1 | NTPCR | ENSPPYP00000001712 | ENSPPYP00000000108 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside-triphosphatase, cancer-related. | 0.529 |
| CTPS2 | AK9 | ENSPPYP00000022544 | ENSPPYP00000018934 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | AK9 isoform 2. | 0.939 |
| CTPS2 | CTPS1 | ENSPPYP00000022544 | ENSPPYP00000001712 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.991 |
| CTPS2 | ITPA | ENSPPYP00000022544 | ENSPPYP00000012088 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.638 |
| CTPS2 | NME4 | ENSPPYP00000022544 | ENSPPYP00000007822 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase. | 0.946 |
