STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)    
Predicted Functional Partners:
H3-4
Histone H3; Belongs to the histone H3 family.
   
 0.958
LOC100436122-8
Histone H3.1.
   
 0.953
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.947
HNRNPL
LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein L.
    
 
 0.886
HNRNPLL
Heterogeneous nuclear ribonucleoprotein L like.
    
 
 0.886
LOC100449918
HIST2H3C isoform 1.
   
 0.881
H3C13
Histone H3.
   
 0.881
HTT
HTT isoform 1.
   
 0.871
HIST2H2BE
Histone H2B; Belongs to the histone H2B family.
    
 0.850
LOC100436122-6
Histone H3.1.
   
 0.832
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.