Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCR8C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (355 aa)    
Predicted Functional Partners:
CCL1
C-C motif chemokine.
   
 0.998
CCL5
C-C motif chemokine.
   
 0.968
GNAQ
G protein subunit alpha q.
     
  0.906
CCL8
C-C motif chemokine.
   
 0.899
CXCL12
CXCL12 isoform 2; Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.877
CX3CL1
CX3CL1 isoform 1.
     
 0.860
CCL21
CCL21 isoform 1.
    
 0.857
CXCL10
C-X-C motif chemokine.
    
 0.851
LOC100439906
C-C motif chemokine 4 isoform X4.
   
 0.840
LOC100439532
C-C motif chemokine.
   
 0.839
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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