Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)    
Predicted Functional Partners:
CCL5
C-C motif chemokine.
    
 0.994
CCL17
C-C motif chemokine.
    
 0.966
GNAQ
G protein subunit alpha q.
     
  0.906
CCL21
CCL21 isoform 1.
   
 0.866
CXCL10
C-X-C motif chemokine.
    
 0.863
LOC100439532
C-C motif chemokine.
    
 0.858
LOC100439906
C-C motif chemokine 4 isoform X4.
    
 0.858
LOC100460653
C-C motif chemokine.
    
 0.858
CR201_G0055603
C-C motif chemokine.
    
 0.858
CXCL12
CXCL12 isoform 2; Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.844
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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