STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DBR1Debranching RNA lariats 1. (547 aa)    
Predicted Functional Partners:
DHX38
DHX38 isoform 1.
    
 
 0.846
ATG4A
Cysteine protease ATG4A; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms (By similarity).
      
 0.664
METTL9
METTL9 isoform 3.
 
      0.560
CWF19L1
CWF19-like protein 1; Belongs to the CWF19 family.
   
 
0.551
GPATCH11
GPATCH11 isoform 1.
   
 
 0.551
XPO5
XPO5 isoform 1.
   
  
 0.462
PPARGC1B
PPARGC1B isoform 1.
      
 0.434
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
  
 0.425
PRPF18
Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing.
    
 
 0.411
CWF19L2
CWF19L2 isoform 1.
   
  
 0.408
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.