| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT1 | CDC42 | ENSPPYP00000007036 | ENSPPYP00000002031 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Cell division cycle 42. | 0.819 |
| AKT1 | CR201_G0037390 | ENSPPYP00000007036 | ENSPPYP00000010903 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | PIK3R2 isoform 1. | 0.964 |
| AKT1 | EGFR | ENSPPYP00000007036 | ENSPPYP00000019671 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Receptor protein-tyrosine kinase. | 0.896 |
| AKT1 | HRAS | ENSPPYP00000007036 | ENSPPYP00000003333 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | HRas proto-oncogene, GTPase. | 0.586 |
| AKT1 | IRS4 | ENSPPYP00000007036 | ENSPPYP00000023087 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Insulin receptor substrate 4. | 0.692 |
| AKT1 | KRAS | ENSPPYP00000007036 | ENSPPYP00000004987 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | KRAS proto-oncogene, GTPase. | 0.664 |
| AKT1 | PIK3CA | ENSPPYP00000007036 | ENSPPYP00000023529 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.996 |
| AKT1 | PIK3CB | ENSPPYP00000007036 | ENSPPYP00000015827 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.990 |
| AKT1 | PIK3R1 | ENSPPYP00000007036 | ENSPPYP00000017341 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.992 |
| AKT1 | PIK3R3 | ENSPPYP00000007036 | ENSPPYP00000001627 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | T0148502 isoform 1. | 0.955 |
| CDC42 | AKT1 | ENSPPYP00000002031 | ENSPPYP00000007036 | Cell division cycle 42. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.819 |
| CDC42 | CR201_G0037390 | ENSPPYP00000002031 | ENSPPYP00000010903 | Cell division cycle 42. | PIK3R2 isoform 1. | 0.965 |
| CDC42 | EGFR | ENSPPYP00000002031 | ENSPPYP00000019671 | Cell division cycle 42. | Receptor protein-tyrosine kinase. | 0.704 |
| CDC42 | PIK3CA | ENSPPYP00000002031 | ENSPPYP00000023529 | Cell division cycle 42. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.983 |
| CDC42 | PIK3CB | ENSPPYP00000002031 | ENSPPYP00000015827 | Cell division cycle 42. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.994 |
| CDC42 | PIK3R1 | ENSPPYP00000002031 | ENSPPYP00000017341 | Cell division cycle 42. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.988 |
| CDC42 | PIK3R3 | ENSPPYP00000002031 | ENSPPYP00000001627 | Cell division cycle 42. | T0148502 isoform 1. | 0.965 |
| CR201_G0037390 | AKT1 | ENSPPYP00000010903 | ENSPPYP00000007036 | PIK3R2 isoform 1. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.964 |
| CR201_G0037390 | CDC42 | ENSPPYP00000010903 | ENSPPYP00000002031 | PIK3R2 isoform 1. | Cell division cycle 42. | 0.965 |
| CR201_G0037390 | EGFR | ENSPPYP00000010903 | ENSPPYP00000019671 | PIK3R2 isoform 1. | Receptor protein-tyrosine kinase. | 0.994 |
