node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO2 | CYFIP1 | ENSPPYP00000021212 | ENSPPYP00000007096 | Eukaryotic translation initiation factor 2C. | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.504 |
AGO2 | ENSPPYP00000023629 | ENSPPYP00000021212 | ENSPPYP00000023629 | Eukaryotic translation initiation factor 2C. | annotation not available | 0.949 |
AGO2 | FMR1 | ENSPPYP00000021212 | ENSPPYP00000023279 | Eukaryotic translation initiation factor 2C. | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | 0.834 |
AGO2 | FXR1 | ENSPPYP00000021212 | ENSPPYP00000016024 | Eukaryotic translation initiation factor 2C. | FMR1 autosomal homolog 1. | 0.752 |
AGO2 | FXR2 | ENSPPYP00000021212 | ENSPPYP00000008919 | Eukaryotic translation initiation factor 2C. | FXR2 isoform 2. | 0.693 |
AGO2 | G3BP1 | ENSPPYP00000021212 | ENSPPYP00000017869 | Eukaryotic translation initiation factor 2C. | Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...] | 0.469 |
CYFIP1 | AGO2 | ENSPPYP00000007096 | ENSPPYP00000021212 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Eukaryotic translation initiation factor 2C. | 0.504 |
CYFIP1 | CYFIP2 | ENSPPYP00000007096 | ENSPPYP00000017891 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | 0.968 |
CYFIP1 | FMR1 | ENSPPYP00000007096 | ENSPPYP00000023279 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | 0.992 |
CYFIP1 | FXR1 | ENSPPYP00000007096 | ENSPPYP00000016024 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | FMR1 autosomal homolog 1. | 0.988 |
CYFIP1 | FXR2 | ENSPPYP00000007096 | ENSPPYP00000008919 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | FXR2 isoform 2. | 0.909 |
CYFIP1 | NUFIP2 | ENSPPYP00000007096 | ENSPPYP00000009131 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | NUFIP2 isoform 1. | 0.655 |
CYFIP2 | CYFIP1 | ENSPPYP00000017891 | ENSPPYP00000007096 | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.968 |
CYFIP2 | FMR1 | ENSPPYP00000017891 | ENSPPYP00000023279 | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | 0.986 |
CYFIP2 | FXR1 | ENSPPYP00000017891 | ENSPPYP00000016024 | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | FMR1 autosomal homolog 1. | 0.988 |
CYFIP2 | FXR2 | ENSPPYP00000017891 | ENSPPYP00000008919 | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | FXR2 isoform 2. | 0.871 |
CYFIP2 | NUFIP2 | ENSPPYP00000017891 | ENSPPYP00000009131 | Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | NUFIP2 isoform 1. | 0.659 |
ENSPPYP00000023629 | AGO2 | ENSPPYP00000023629 | ENSPPYP00000021212 | annotation not available | Eukaryotic translation initiation factor 2C. | 0.949 |
ENSPPYP00000023629 | FMR1 | ENSPPYP00000023629 | ENSPPYP00000023279 | annotation not available | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export. Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons. Stabilizes the scaffolding postsynaptic density protein DLG4/PSD-95 [...] | 0.752 |
ENSPPYP00000023629 | FXR1 | ENSPPYP00000023629 | ENSPPYP00000016024 | annotation not available | FMR1 autosomal homolog 1. | 0.752 |