STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX2SRY-box transcription factor 2. (319 aa)    
Predicted Functional Partners:
POU5F1
POU domain protein.
    
 0.997
KLF4
Kruppel like factor 4.
    
 0.987
SALL4
SALL4 isoform 1.
   
 0.975
LOC100432049
NANOG isoform 2.
    
 0.972
ENSPPYP00000005886
annotation not available
    
 0.972
PRDM14
PRDM14 isoform 1.
    
 0.963
SMAD3
Mothers against decapentaplegic homolog.
    
 0.942
POU2F1
POU domain protein.
   
 0.924
ZSCAN10
ZSCAN10 isoform 1.
    
 0.922
FOXH1
FOXH1 isoform 1.
   
 0.907
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.