Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HTR3CHTR3C isoform 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (447 aa)    
Predicted Functional Partners:
HTR3A
5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
0.880
HTR3B
HTR3B isoform 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
0.668
CR201_G0010589
HTR3D isoform 1.
  
  
0.625
HTR3E
5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
  
0.582
C22orf31
Chromosome 22 open reading frame 31.
  
     0.500
METTL25
METTL25 isoform 1.
    
   0.491
TMEM104
Transmembrane protein 104.
    
   0.491
ARL6IP5
PRA1 family protein 3; Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity- dependent manner. May be involved in membrane traffic.
    
   0.490
WDR87
WDR87 isoform 1.
  
 
   0.443
AHSP
Alpha hemoglobin stabilizing protein.
  
     0.431
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.