ENSPPYP00000016040 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSPPYP00000016040

LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5. (166 aa)

Predicted Functional Partners:

SUGT1

0.968

DKFZp468G2216

0.954

AKT3

0.946

AKT2

0.946

RIPK3

0.931

AHR

0.928

RIPK1

0.925

MLKL

0.923

NLRP3

0.918

RIPK2

0.918

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	ENSPPYP00000016040	ENSPPYP00000019906	ENSPPYP00000016040	T0067486 isoform 1.	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	0.928
AKT2	AKT3	ENSPPYP00000011178	ENSPPYP00000000057	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.955
AKT2	ENSPPYP00000016040	ENSPPYP00000011178	ENSPPYP00000016040	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	0.946
AKT3	AKT2	ENSPPYP00000000057	ENSPPYP00000011178	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.955
AKT3	ENSPPYP00000016040	ENSPPYP00000000057	ENSPPYP00000016040	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	0.946
DKFZp468G2216	ENSPPYP00000016040	ENSPPYP00000022865	ENSPPYP00000016040	AR isoform 8.	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	0.954
ENSPPYP00000016040	AHR	ENSPPYP00000016040	ENSPPYP00000019906	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	T0067486 isoform 1.	0.928
ENSPPYP00000016040	AKT2	ENSPPYP00000016040	ENSPPYP00000011178	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.946
ENSPPYP00000016040	AKT3	ENSPPYP00000016040	ENSPPYP00000000057	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.946
ENSPPYP00000016040	DKFZp468G2216	ENSPPYP00000016040	ENSPPYP00000022865	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	AR isoform 8.	0.954
ENSPPYP00000016040	MLKL	ENSPPYP00000016040	ENSPPYP00000008524	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	MLKL isoform 4.	0.923
ENSPPYP00000016040	NLRP3	ENSPPYP00000016040	ENSPPYP00000000034	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	NLRP3 isoform 2.	0.918
ENSPPYP00000016040	RIPK1	ENSPPYP00000016040	ENSPPYP00000018096	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Receptor interacting serine/threonine kinase 1.	0.925
ENSPPYP00000016040	RIPK2	ENSPPYP00000016040	ENSPPYP00000021009	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.918
ENSPPYP00000016040	RIPK3	ENSPPYP00000016040	ENSPPYP00000006485	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Receptor interacting serine/threonine kinase 3.	0.931
ENSPPYP00000016040	SUGT1	ENSPPYP00000016040	ENSPPYP00000006144	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.968
MLKL	ENSPPYP00000016040	ENSPPYP00000008524	ENSPPYP00000016040	MLKL isoform 4.	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	0.923
MLKL	NLRP3	ENSPPYP00000008524	ENSPPYP00000000034	MLKL isoform 4.	NLRP3 isoform 2.	0.918
MLKL	RIPK1	ENSPPYP00000008524	ENSPPYP00000018096	MLKL isoform 4.	Receptor interacting serine/threonine kinase 1.	0.894
MLKL	RIPK3	ENSPPYP00000008524	ENSPPYP00000006485	MLKL isoform 4.	Receptor interacting serine/threonine kinase 3.	0.999