ENSPPYP00000016040 protein (Pongo abelii) - STRING interaction network

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000001359	ENSPPYP00000016040	ENSPPYP00000001359	ENSPPYP00000016040	annotation not available	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	0.667
ENSPPYP00000001359	FKBP4	ENSPPYP00000001359	ENSPPYP00000004732	annotation not available	Peptidylprolyl isomerase.	0.673
ENSPPYP00000001359	FKBP5	ENSPPYP00000001359	ENSPPYP00000018489	annotation not available	Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (By similarity).	0.673
ENSPPYP00000001359	HSP90B1	ENSPPYP00000001359	ENSPPYP00000023483	annotation not available	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.582
ENSPPYP00000001359	HSPD1	ENSPPYP00000001359	ENSPPYP00000014577	annotation not available	60 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...]	0.465
ENSPPYP00000001359	PPID	ENSPPYP00000001359	ENSPPYP00000016942	annotation not available	Peptidylprolyl isomerase D.	0.831
ENSPPYP00000001359	PTGES3	ENSPPYP00000001359	ENSPPYP00000005319	annotation not available	Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.	0.900
ENSPPYP00000001359	STIP1	ENSPPYP00000001359	ENSPPYP00000003602	annotation not available	STIP1 isoform 2.	0.907
ENSPPYP00000016040	ENSPPYP00000001359	ENSPPYP00000016040	ENSPPYP00000001359	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	annotation not available	0.667
ENSPPYP00000016040	FKBP4	ENSPPYP00000016040	ENSPPYP00000004732	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Peptidylprolyl isomerase.	0.725
ENSPPYP00000016040	FKBP5	ENSPPYP00000016040	ENSPPYP00000018489	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (By similarity).	0.677
ENSPPYP00000016040	HSP90B1	ENSPPYP00000016040	ENSPPYP00000023483	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family.	0.762
ENSPPYP00000016040	HSPA4	ENSPPYP00000016040	ENSPPYP00000017643	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.	0.684
ENSPPYP00000016040	HSPD1	ENSPPYP00000016040	ENSPPYP00000014577	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	60 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...]	0.664
ENSPPYP00000016040	PPID	ENSPPYP00000016040	ENSPPYP00000016942	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Peptidylprolyl isomerase D.	0.730
ENSPPYP00000016040	PTGES3	ENSPPYP00000016040	ENSPPYP00000005319	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.	0.791
ENSPPYP00000016040	STIP1	ENSPPYP00000016040	ENSPPYP00000003602	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	STIP1 isoform 2.	0.825
ENSPPYP00000016040	SUGT1	ENSPPYP00000016040	ENSPPYP00000006144	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.708
FKBP4	ENSPPYP00000001359	ENSPPYP00000004732	ENSPPYP00000001359	Peptidylprolyl isomerase.	annotation not available	0.673
FKBP4	ENSPPYP00000016040	ENSPPYP00000004732	ENSPPYP00000016040	Peptidylprolyl isomerase.	LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5.	0.725