Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (367 aa)    
Predicted Functional Partners:
PCYT1B
PCYT1B isoform 3.
  
 
0.999
CHKA
CHKA isoform 2.
   
 
 0.992
CEPT1
Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.964
CHPT1
CHPT1 isoform 3; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.962
PHOSPHO1
Phosphoethanolamine/phosphocholine phosphatase.
     
 0.918
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
  0.917
MAPK8
Mitogen-activated protein kinase.
     
 0.901
MAPK10
Mitogen-activated protein kinase.
     
 0.901
MAPK9
Mitogen-activated protein kinase.
     
 0.901
SELENOI
Ethanolaminephosphotransferase 1; Catalyzes phosphatidylethanolamine biosynthesis from CDP- ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via 'Kennedy' pathway (By similarity).
     
 0.753
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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