DRD5 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD1	DRD5	ENSPPYP00000017976	ENSPPYP00000016314	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	0.948
DRD1	GNAL	ENSPPYP00000017976	ENSPPYP00000010095	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	GNAL isoform 3.	0.961
DRD1	GNAQ	ENSPPYP00000017976	ENSPPYP00000021633	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha q.	0.941
DRD1	GNAS	ENSPPYP00000017976	ENSPPYP00000012485	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	GNAS isoform 2.	0.945
DRD1	GNB1	ENSPPYP00000017976	ENSPPYP00000002307	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.979
DRD1	GNB2	ENSPPYP00000017976	ENSPPYP00000019528	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	GNB2 isoform 1.	0.946
DRD1	GNB3	ENSPPYP00000017976	ENSPPYP00000004790	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.943
DRD1	GNG12	ENSPPYP00000017976	ENSPPYP00000001459	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.939
DRD1	GNG4	ENSPPYP00000017976	ENSPPYP00000000094	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.944
DRD5	DRD1	ENSPPYP00000016314	ENSPPYP00000017976	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.948
DRD5	GNAL	ENSPPYP00000016314	ENSPPYP00000010095	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	GNAL isoform 3.	0.948
DRD5	GNAQ	ENSPPYP00000016314	ENSPPYP00000021633	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha q.	0.941
DRD5	GNAS	ENSPPYP00000016314	ENSPPYP00000012485	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	GNAS isoform 2.	0.945
DRD5	GNB1	ENSPPYP00000016314	ENSPPYP00000002307	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.929
DRD5	GNB2	ENSPPYP00000016314	ENSPPYP00000019528	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	GNB2 isoform 1.	0.815
DRD5	GNB3	ENSPPYP00000016314	ENSPPYP00000004790	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.803
DRD5	GNG12	ENSPPYP00000016314	ENSPPYP00000001459	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.790
DRD5	GNG4	ENSPPYP00000016314	ENSPPYP00000000094	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.809
DRD5	TMEM128	ENSPPYP00000016314	ENSPPYP00000016312	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	Transmembrane protein 128.	0.903
GNAL	DRD1	ENSPPYP00000010095	ENSPPYP00000017976	GNAL isoform 3.	DRD1 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.961