| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABCG2 | BHMT | ENSPPYP00000016661 | ENSPPYP00000017424 | ABCG2 isoform 2. | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | 0.496 |
| ABCG2 | HPRT1 | ENSPPYP00000016661 | ENSPPYP00000023211 | ABCG2 isoform 2. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.497 |
| ABCG2 | PAAF1 | ENSPPYP00000016661 | ENSPPYP00000004190 | ABCG2 isoform 2. | Proteasomal ATPase associated factor 1. | 0.486 |
| ABCG2 | SLC22A11 | ENSPPYP00000016661 | ENSPPYP00000003588 | ABCG2 isoform 2. | SLC22A11 isoform 1. | 0.492 |
| ABCG2 | SLC22A12 | ENSPPYP00000016661 | ENSPPYP00000003586 | ABCG2 isoform 2. | SLC22A12 isoform 2. | 0.524 |
| ABCG2 | SLC22A6 | ENSPPYP00000016661 | ENSPPYP00000003625 | ABCG2 isoform 2. | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3- dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxy [...] | 0.426 |
| ABCG2 | SLC22A8 | ENSPPYP00000016661 | ENSPPYP00000003623 | ABCG2 isoform 2. | Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. | 0.530 |
| ABCG2 | SLC2A9 | ENSPPYP00000016661 | ENSPPYP00000016315 | ABCG2 isoform 2. | Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules (By similarity). Does not transport glucose, fructose or galactose (By similarity). | 0.620 |
| ABCG2 | USP1 | ENSPPYP00000016661 | ENSPPYP00000001497 | ABCG2 isoform 2. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.490 |
| BHMT | ABCG2 | ENSPPYP00000017424 | ENSPPYP00000016661 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | ABCG2 isoform 2. | 0.496 |
| BHMT | HPRT1 | ENSPPYP00000017424 | ENSPPYP00000023211 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.613 |
| BHMT | PAAF1 | ENSPPYP00000017424 | ENSPPYP00000004190 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | Proteasomal ATPase associated factor 1. | 0.610 |
| BHMT | SLC2A9 | ENSPPYP00000017424 | ENSPPYP00000016315 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules (By similarity). Does not transport glucose, fructose or galactose (By similarity). | 0.675 |
| BHMT | USP1 | ENSPPYP00000017424 | ENSPPYP00000001497 | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.655 |
| HPRT1 | ABCG2 | ENSPPYP00000023211 | ENSPPYP00000016661 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | ABCG2 isoform 2. | 0.497 |
| HPRT1 | BHMT | ENSPPYP00000023211 | ENSPPYP00000017424 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Betaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline (By similarity). | 0.613 |
| HPRT1 | PAAF1 | ENSPPYP00000023211 | ENSPPYP00000004190 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Proteasomal ATPase associated factor 1. | 0.556 |
| HPRT1 | SLC2A9 | ENSPPYP00000023211 | ENSPPYP00000016315 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules (By similarity). Does not transport glucose, fructose or galactose (By similarity). | 0.668 |
| HPRT1 | USP1 | ENSPPYP00000023211 | ENSPPYP00000001497 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.560 |
| PAAF1 | ABCG2 | ENSPPYP00000004190 | ENSPPYP00000016661 | Proteasomal ATPase associated factor 1. | ABCG2 isoform 2. | 0.486 |
