STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGI2Leucine rich repeat LGI family member 2. (545 aa)    
Predicted Functional Partners:
FBXL17
FBXL17 isoform 1.
   
 
 0.801
SMOC1
SMOC1 isoform 2.
      
 0.785
ADAM23
ADAM23 isoform 1.
     
 0.773
ADAM22
ADAM22 isoform 4.
     
 0.765
CR201_G0023722
ADAM11 isoform 1.
     
 0.655
AGRP
Agouti related neuropeptide.
      
 0.631
ADIPOQ
Adiponectin, C1Q and collagen domain containing.
    
 
 0.536
ZDBF2
ZDBF2 isoform 1.
     
 0.506
PGK1
Phosphoglycerate kinase 1; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility.
    
 
 0.460
CECR2
CECR2 isoform 2.
    
 0.424
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.