| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CREBBP | EP300 | ENSPPYP00000007974 | ENSPPYP00000013236 | CREBBP isoform 1. | EP300 isoform 1. | 0.999 |
| CREBBP | KAT2B | ENSPPYP00000007974 | ENSPPYP00000015742 | CREBBP isoform 1. | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | 0.997 |
| CREBBP | MAML1 | ENSPPYP00000007974 | ENSPPYP00000018042 | CREBBP isoform 1. | MAML1 isoform 1. | 0.956 |
| CREBBP | MAML2 | ENSPPYP00000007974 | ENSPPYP00000004339 | CREBBP isoform 1. | MAML2 isoform 2. | 0.937 |
| CREBBP | NCOR2 | ENSPPYP00000007974 | ENSPPYP00000005808 | CREBBP isoform 1. | NCOR2 isoform 6. | 0.756 |
| CREBBP | NOTCH3 | ENSPPYP00000007974 | ENSPPYP00000010835 | CREBBP isoform 1. | NOTCH3 isoform 1. | 0.406 |
| CREBBP | RBPJ | ENSPPYP00000007974 | ENSPPYP00000016373 | CREBBP isoform 1. | Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling [...] | 0.971 |
| CREBBP | SNW1 | ENSPPYP00000007974 | ENSPPYP00000006859 | CREBBP isoform 1. | SNW domain-containing protein 1; Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, [...] | 0.834 |
| EP300 | CREBBP | ENSPPYP00000013236 | ENSPPYP00000007974 | EP300 isoform 1. | CREBBP isoform 1. | 0.999 |
| EP300 | KAT2B | ENSPPYP00000013236 | ENSPPYP00000015742 | EP300 isoform 1. | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. | 0.999 |
| EP300 | MAML1 | ENSPPYP00000013236 | ENSPPYP00000018042 | EP300 isoform 1. | MAML1 isoform 1. | 0.991 |
| EP300 | MAML2 | ENSPPYP00000013236 | ENSPPYP00000004339 | EP300 isoform 1. | MAML2 isoform 2. | 0.941 |
| EP300 | NCOR2 | ENSPPYP00000013236 | ENSPPYP00000005808 | EP300 isoform 1. | NCOR2 isoform 6. | 0.698 |
| EP300 | NOTCH3 | ENSPPYP00000013236 | ENSPPYP00000010835 | EP300 isoform 1. | NOTCH3 isoform 1. | 0.593 |
| EP300 | RBPJ | ENSPPYP00000013236 | ENSPPYP00000016373 | EP300 isoform 1. | Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling [...] | 0.964 |
| EP300 | SNW1 | ENSPPYP00000013236 | ENSPPYP00000006859 | EP300 isoform 1. | SNW domain-containing protein 1; Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, [...] | 0.816 |
| EP300 | SPEN | ENSPPYP00000013236 | ENSPPYP00000002129 | EP300 isoform 1. | SPEN isoform 1. | 0.594 |
| HES1 | MAML1 | ENSPPYP00000016129 | ENSPPYP00000018042 | HES1 isoform 1. | MAML1 isoform 1. | 0.673 |
| HES1 | MAML2 | ENSPPYP00000016129 | ENSPPYP00000004339 | HES1 isoform 1. | MAML2 isoform 2. | 0.520 |
| HES1 | NOTCH3 | ENSPPYP00000016129 | ENSPPYP00000010835 | HES1 isoform 1. | NOTCH3 isoform 1. | 0.833 |
