STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRL3ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family. (1239 aa)    
Predicted Functional Partners:
FLRT3
Leucine-rich repeat transmembrane protein FLRT3; Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (By similarity). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expres [...]
    
 
 0.973
TENM2
TENM2 isoform 3.
    
 
 0.958
UNC5D
UNC5D isoform 4.
   
 
 0.927
TENM4
TENM4 isoform 2.
    
 
 0.923
TENM3
TENM3 isoform 3.
    
 
 0.920
TENM1
Teneurin transmembrane protein 1.
    
 
 0.913
SZRD1
SUZ domain-containing protein 1.
    
 
 0.893
VEGFB
Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.
    
 
 0.893
CR201_G0037836
TENM3 isoform 2.
    
 
 0.893
VEGFA
VEGFA isoform 3; Belongs to the PDGF/VEGF growth factor family.
    
 
 0.893
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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