ADGRL3 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL3	CTNND2	ENSPPYP00000016465	ENSPPYP00000017145	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	CTNND2 isoform 1.	0.890
ADGRL3	FEZ2	ENSPPYP00000016465	ENSPPYP00000014207	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	FEZ2 isoform 2.	0.860
ADGRL3	FLRT3	ENSPPYP00000016465	ENSPPYP00000011984	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Leucine-rich repeat transmembrane protein FLRT3; Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (By similarity). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expres [...]	0.865
ADGRL3	FRMD6	ENSPPYP00000016465	ENSPPYP00000006604	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	FERM domain containing 6.	0.745
ADGRL3	GNB1	ENSPPYP00000016465	ENSPPYP00000002307	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.745
ADGRL3	GNB2	ENSPPYP00000016465	ENSPPYP00000019528	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	GNB2 isoform 1.	0.745
ADGRL3	GNB3	ENSPPYP00000016465	ENSPPYP00000004790	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	G protein subunit beta 3.	0.745
ADGRL3	GNB5	ENSPPYP00000016465	ENSPPYP00000007348	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.762
ADGRL3	SRBD1	ENSPPYP00000016465	ENSPPYP00000013898	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	S1 RNA-binding domain-containing protein 1.	0.888
ADGRL3	TENM2	ENSPPYP00000016465	ENSPPYP00000017931	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	TENM2 isoform 3.	0.789
CTNND2	ADGRL3	ENSPPYP00000017145	ENSPPYP00000016465	CTNND2 isoform 1.	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.890
CTNND2	FEZ2	ENSPPYP00000017145	ENSPPYP00000014207	CTNND2 isoform 1.	FEZ2 isoform 2.	0.864
CTNND2	SRBD1	ENSPPYP00000017145	ENSPPYP00000013898	CTNND2 isoform 1.	S1 RNA-binding domain-containing protein 1.	0.864
FEZ2	ADGRL3	ENSPPYP00000014207	ENSPPYP00000016465	FEZ2 isoform 2.	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.860
FEZ2	CTNND2	ENSPPYP00000014207	ENSPPYP00000017145	FEZ2 isoform 2.	CTNND2 isoform 1.	0.864
FEZ2	SRBD1	ENSPPYP00000014207	ENSPPYP00000013898	FEZ2 isoform 2.	S1 RNA-binding domain-containing protein 1.	0.888
FLRT3	ADGRL3	ENSPPYP00000011984	ENSPPYP00000016465	Leucine-rich repeat transmembrane protein FLRT3; Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (By similarity). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expres [...]	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.865
FRMD6	ADGRL3	ENSPPYP00000006604	ENSPPYP00000016465	FERM domain containing 6.	ADGRL3 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.745
FRMD6	GNB1	ENSPPYP00000006604	ENSPPYP00000002307	FERM domain containing 6.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.736
FRMD6	GNB2	ENSPPYP00000006604	ENSPPYP00000019528	FERM domain containing 6.	GNB2 isoform 1.	0.626