HOPX protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

HOPX

HOPX isoform 2. (87 aa)

Predicted Functional Partners:

EVX2

0.565

OTP

0.551

SCGN

0.539

EN1

0.499

LIX1

0.499

CALB2

0.490

PTPRZ1

0.474

ATP1A2

0.445

HDAC2

0.441

SLCO1C1

0.434

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1A2	CALB2	ENSPPYP00000000749	ENSPPYP00000023738	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	CALB2 isoform 1.	0.734
ATP1A2	HOPX	ENSPPYP00000000749	ENSPPYP00000016473	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	HOPX isoform 2.	0.445
ATP1A2	LIX1	ENSPPYP00000000749	ENSPPYP00000017503	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Limb and CNS expressed 1.	0.738
ATP1A2	SCGN	ENSPPYP00000000749	ENSPPYP00000018218	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Secretagogin, EF-hand calcium binding protein.	0.766
ATP1A2	SLCO1C1	ENSPPYP00000000749	ENSPPYP00000004965	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	Solute carrier organic anion transporter family member.	0.801
CALB2	ATP1A2	ENSPPYP00000023738	ENSPPYP00000000749	CALB2 isoform 1.	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	0.734
CALB2	HOPX	ENSPPYP00000023738	ENSPPYP00000016473	CALB2 isoform 1.	HOPX isoform 2.	0.490
CALB2	LIX1	ENSPPYP00000023738	ENSPPYP00000017503	CALB2 isoform 1.	Limb and CNS expressed 1.	0.710
CALB2	SLCO1C1	ENSPPYP00000023738	ENSPPYP00000004965	CALB2 isoform 1.	Solute carrier organic anion transporter family member.	0.775
EN1	HOPX	ENSPPYP00000014275	ENSPPYP00000016473	Homeobox protein engrailed-like.	HOPX isoform 2.	0.499
EVX2	HOPX	ENSPPYP00000014467	ENSPPYP00000016473	EVX2 isoform 1.	HOPX isoform 2.	0.565
HDAC2	HOPX	ENSPPYP00000018964	ENSPPYP00000016473	Histone deacetylase 2.	HOPX isoform 2.	0.441
HOPX	ATP1A2	ENSPPYP00000016473	ENSPPYP00000000749	HOPX isoform 2.	Sodium/potassium-transporting ATPase subunit alpha-2; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity). Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.	0.445
HOPX	CALB2	ENSPPYP00000016473	ENSPPYP00000023738	HOPX isoform 2.	CALB2 isoform 1.	0.490
HOPX	EN1	ENSPPYP00000016473	ENSPPYP00000014275	HOPX isoform 2.	Homeobox protein engrailed-like.	0.499
HOPX	EVX2	ENSPPYP00000016473	ENSPPYP00000014467	HOPX isoform 2.	EVX2 isoform 1.	0.565
HOPX	HDAC2	ENSPPYP00000016473	ENSPPYP00000018964	HOPX isoform 2.	Histone deacetylase 2.	0.441
HOPX	LIX1	ENSPPYP00000016473	ENSPPYP00000017503	HOPX isoform 2.	Limb and CNS expressed 1.	0.499
HOPX	OTP	ENSPPYP00000016473	ENSPPYP00000017415	HOPX isoform 2.	Orthopedia homeobox.	0.551
HOPX	PTPRZ1	ENSPPYP00000016473	ENSPPYP00000020130	HOPX isoform 2.	PTPRZ1 isoform 1.	0.474