STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH7ADH7 isoform 2. (387 aa)    
Predicted Functional Partners:
ALDH1A1
ALDH1A1 isoform 5; Belongs to the aldehyde dehydrogenase family.
  
 0.965
ALDH3A1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.955
ALDH3B1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.938
CYP2E1
CYP2E1 isoform 1; Belongs to the cytochrome P450 family.
  
 
 0.931
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
    
 0.926
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
 0.919
ESD
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.919
MAOA
Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).
   
 
 0.915
RETSAT
RETSAT isoform 1.
  
 
 0.912
BCO1
BCO1 isoform 1.
   
 
 0.906
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.