Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANP32E | EP400 | ENSPPYP00000001060 | ENSPPYP00000005850 | ANP32E isoform 5. | EP400 isoform 3. | 0.710 |
ANP32E | H2AZ1 | ENSPPYP00000001060 | ENSPPYP00000016702 | ANP32E isoform 5. | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.962 |
ANP32E | HIST2H2BE | ENSPPYP00000001060 | ENSPPYP00000001071 | ANP32E isoform 5. | Histone H2B; Belongs to the histone H2B family. | 0.507 |
ANP32E | KAT5 | ENSPPYP00000001060 | ENSPPYP00000003532 | ANP32E isoform 5. | Histone acetyltransferase KAT5; Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replica [...] | 0.619 |
ANP32E | SRCAP | ENSPPYP00000001060 | ENSPPYP00000008230 | ANP32E isoform 5. | T0121283 isoform 1. | 0.470 |
ANP32E | VPS72 | ENSPPYP00000001060 | ENSPPYP00000001020 | ANP32E isoform 5. | Vacuolar protein sorting-associated protein 72 homolog; Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. | 0.852 |
CDK7 | H2AZ1 | ENSPPYP00000017348 | ENSPPYP00000016702 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.900 |
CDK7 | POLR2C | ENSPPYP00000017348 | ENSPPYP00000008349 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | RNA polymerase II subunit C. | 0.909 |
EP400 | ANP32E | ENSPPYP00000005850 | ENSPPYP00000001060 | EP400 isoform 3. | ANP32E isoform 5. | 0.710 |
EP400 | H2AZ1 | ENSPPYP00000005850 | ENSPPYP00000016702 | EP400 isoform 3. | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.913 |
EP400 | HIST2H2BE | ENSPPYP00000005850 | ENSPPYP00000001071 | EP400 isoform 3. | Histone H2B; Belongs to the histone H2B family. | 0.484 |
EP400 | KAT5 | ENSPPYP00000005850 | ENSPPYP00000003532 | EP400 isoform 3. | Histone acetyltransferase KAT5; Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replica [...] | 0.999 |
EP400 | POLR2C | ENSPPYP00000005850 | ENSPPYP00000008349 | EP400 isoform 3. | RNA polymerase II subunit C. | 0.434 |
EP400 | RUVBL1 | ENSPPYP00000005850 | ENSPPYP00000015029 | EP400 isoform 3. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.997 |
EP400 | RUVBL2 | ENSPPYP00000005850 | ENSPPYP00000011437 | EP400 isoform 3. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.998 |
EP400 | SRCAP | ENSPPYP00000005850 | ENSPPYP00000008230 | EP400 isoform 3. | T0121283 isoform 1. | 0.661 |
EP400 | VPS72 | ENSPPYP00000005850 | ENSPPYP00000001020 | EP400 isoform 3. | Vacuolar protein sorting-associated protein 72 homolog; Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. | 0.979 |
H2AZ1 | ANP32E | ENSPPYP00000016702 | ENSPPYP00000001060 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | ANP32E isoform 5. | 0.962 |
H2AZ1 | CDK7 | ENSPPYP00000016702 | ENSPPYP00000017348 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | CDK7 isoform 1; Belongs to the protein kinase superfamily. | 0.900 |
H2AZ1 | EP400 | ENSPPYP00000016702 | ENSPPYP00000005850 | Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | EP400 isoform 3. | 0.913 |
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