Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PITX2Homeobox protein. (317 aa)    
Predicted Functional Partners:
PITX3
Homeobox protein.
   
   0.963
CTNNB1
CTNNB1 isoform 2.
    
 
 0.819
AHCYL1
Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.
    
   0.788
FOXC1
FOXC1 isoform 1.
    
 
 0.751
PITX1
Homeobox protein.
   
   0.693
LEFTY2
Left-right determination factor.
   
  
 0.669
LEF1
Lymphoid enhancer binding factor 1.
    
 
 0.658
TRIM25
Tripartite motif containing 25.
    
   0.637
ENSPPYP00000000171
Left-right determination factor 1 isoform X1.
   
  
 0.616
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
      
 0.567
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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