| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCNA1 | CCNA2 | ENSPPYP00000006017 | ENSPPYP00000016798 | CCNA1 isoform 3; Belongs to the cyclin family. | CCNA2 isoform 1; Belongs to the cyclin family. | 0.994 |
| CCNA1 | CDC20 | ENSPPYP00000006017 | ENSPPYP00000001678 | CCNA1 isoform 3; Belongs to the cyclin family. | Cell division cycle 20. | 0.978 |
| CCNA1 | CDC6 | ENSPPYP00000006017 | ENSPPYP00000009512 | CCNA1 isoform 3; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.996 |
| CCNA1 | CDK1 | ENSPPYP00000006017 | ENSPPYP00000002808 | CCNA1 isoform 3; Belongs to the cyclin family. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, G [...] | 0.999 |
| CCNA1 | CDK2 | ENSPPYP00000006017 | ENSPPYP00000005283 | CCNA1 isoform 3; Belongs to the cyclin family. | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. | 0.999 |
| CCNA1 | CDKN1A | ENSPPYP00000006017 | ENSPPYP00000018511 | CCNA1 isoform 3; Belongs to the cyclin family. | Cyclin dependent kinase inhibitor 1A. | 0.997 |
| CCNA1 | CDKN1B | ENSPPYP00000006017 | ENSPPYP00000004921 | CCNA1 isoform 3; Belongs to the cyclin family. | Cyclin dependent kinase inhibitor 1B. | 0.997 |
| CCNA1 | CDKN1C | ENSPPYP00000006017 | ENSPPYP00000003407 | CCNA1 isoform 3; Belongs to the cyclin family. | CDKN1C isoform 4. | 0.986 |
| CCNA1 | E2F1 | ENSPPYP00000006017 | ENSPPYP00000012205 | CCNA1 isoform 3; Belongs to the cyclin family. | E2F1 isoform 1. | 0.992 |
| CCNA1 | RB1 | ENSPPYP00000006017 | ENSPPYP00000006102 | CCNA1 isoform 3; Belongs to the cyclin family. | RB1 isoform 1. | 0.992 |
| CCNA2 | CCNA1 | ENSPPYP00000016798 | ENSPPYP00000006017 | CCNA2 isoform 1; Belongs to the cyclin family. | CCNA1 isoform 3; Belongs to the cyclin family. | 0.994 |
| CCNA2 | CDC20 | ENSPPYP00000016798 | ENSPPYP00000001678 | CCNA2 isoform 1; Belongs to the cyclin family. | Cell division cycle 20. | 0.996 |
| CCNA2 | CDC6 | ENSPPYP00000016798 | ENSPPYP00000009512 | CCNA2 isoform 1; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.998 |
| CCNA2 | CDK1 | ENSPPYP00000016798 | ENSPPYP00000002808 | CCNA2 isoform 1; Belongs to the cyclin family. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, G [...] | 0.999 |
| CCNA2 | CDK2 | ENSPPYP00000016798 | ENSPPYP00000005283 | CCNA2 isoform 1; Belongs to the cyclin family. | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. | 0.999 |
| CCNA2 | CDKN1A | ENSPPYP00000016798 | ENSPPYP00000018511 | CCNA2 isoform 1; Belongs to the cyclin family. | Cyclin dependent kinase inhibitor 1A. | 0.997 |
| CCNA2 | CDKN1B | ENSPPYP00000016798 | ENSPPYP00000004921 | CCNA2 isoform 1; Belongs to the cyclin family. | Cyclin dependent kinase inhibitor 1B. | 0.997 |
| CCNA2 | CDKN1C | ENSPPYP00000016798 | ENSPPYP00000003407 | CCNA2 isoform 1; Belongs to the cyclin family. | CDKN1C isoform 4. | 0.993 |
| CCNA2 | E2F1 | ENSPPYP00000016798 | ENSPPYP00000012205 | CCNA2 isoform 1; Belongs to the cyclin family. | E2F1 isoform 1. | 0.996 |
| CCNA2 | RB1 | ENSPPYP00000016798 | ENSPPYP00000006102 | CCNA2 isoform 1; Belongs to the cyclin family. | RB1 isoform 1. | 0.998 |
