STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGST2Microsomal glutathione S-transferase 2. (147 aa)    
Predicted Functional Partners:
MGST1
Microsomal glutathione S-transferase 1.
    
 0.960
CYP2E1
CYP2E1 isoform 1; Belongs to the cytochrome P450 family.
   
 
  0.901
MGST3
MGST3 isoform 3.
     
0.880
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
   
 
 0.842
GPX2
GPX2 isoform 4.
   
 
 0.786
GSTO1
Glutathione S-transferase omega 1.
     
 0.771
PTGES
Prostaglandin E synthase.
    
 0.771
GSTK1
Glutathione S-transferase kappa.
   
 0.766
CHAC2
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.755
GSTP1
Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family.
   
 
 0.748
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.