STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPPYP00000016868annotation not available (85 aa)    
Predicted Functional Partners:
SMAD4
Mothers against decapentaplegic homolog.
   
 0.990
SMURF1
E3 ubiquitin-protein ligase.
    
 0.952
LEMD3
LEMD3 isoform 1.
   
 
 0.891
SMURF2
E3 ubiquitin-protein ligase.
    
 0.847
SMAD6
Mothers against decapentaplegic homolog.
   
 0.771
EP300
EP300 isoform 1.
   
 0.713
STUB1
STIP1 homology and U-box containing protein 1.
   
 0.696
SKIL
Ski-like protein; May have regulatory role in cell division or differentiation in response to extracellular signals.
   
 0.682
SKI
SKI isoform 1.
   
 0.667
YAP1
YAP1 isoform 2.
    
 0.654
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.