| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BMPR1B | CR201_G0000132 | ENSPPYP00000016680 | ENSPPYP00000006021 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | SMAD1 isoform 8. | 0.982 |
| BMPR1B | ENSPPYP00000016868 | ENSPPYP00000016680 | ENSPPYP00000016868 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | annotation not available | 0.836 |
| BMPR1B | SKI | ENSPPYP00000016680 | ENSPPYP00000002297 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | SKI isoform 1. | 0.424 |
| BMPR1B | SMAD2 | ENSPPYP00000016680 | ENSPPYP00000010275 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator [...] | 0.966 |
| BMPR1B | SMAD4 | ENSPPYP00000016680 | ENSPPYP00000010297 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.838 |
| BMPR1B | SMAD5 | ENSPPYP00000016680 | ENSPPYP00000017676 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor- regulated SMAD (R-SMAD) (By similarity). | 0.977 |
| BMPR1B | SMAD6 | ENSPPYP00000016680 | ENSPPYP00000007463 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.887 |
| BMPR1B | SMURF1 | ENSPPYP00000016680 | ENSPPYP00000019458 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | E3 ubiquitin-protein ligase. | 0.838 |
| BMPR1B | SMURF2 | ENSPPYP00000016680 | ENSPPYP00000009604 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | E3 ubiquitin-protein ligase. | 0.658 |
| CR201_G0000132 | BMPR1B | ENSPPYP00000006021 | ENSPPYP00000016680 | SMAD1 isoform 8. | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.982 |
| CR201_G0000132 | ENSPPYP00000016868 | ENSPPYP00000006021 | ENSPPYP00000016868 | SMAD1 isoform 8. | annotation not available | 0.928 |
| CR201_G0000132 | SKI | ENSPPYP00000006021 | ENSPPYP00000002297 | SMAD1 isoform 8. | SKI isoform 1. | 0.896 |
| CR201_G0000132 | SMAD2 | ENSPPYP00000006021 | ENSPPYP00000010275 | SMAD1 isoform 8. | Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator [...] | 0.970 |
| CR201_G0000132 | SMAD4 | ENSPPYP00000006021 | ENSPPYP00000010297 | SMAD1 isoform 8. | Mothers against decapentaplegic homolog. | 0.999 |
| CR201_G0000132 | SMAD5 | ENSPPYP00000006021 | ENSPPYP00000017676 | SMAD1 isoform 8. | Mothers against decapentaplegic homolog 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor- regulated SMAD (R-SMAD) (By similarity). | 0.994 |
| CR201_G0000132 | SMAD6 | ENSPPYP00000006021 | ENSPPYP00000007463 | SMAD1 isoform 8. | Mothers against decapentaplegic homolog. | 0.974 |
| CR201_G0000132 | SMURF1 | ENSPPYP00000006021 | ENSPPYP00000019458 | SMAD1 isoform 8. | E3 ubiquitin-protein ligase. | 0.756 |
| CR201_G0000132 | SMURF2 | ENSPPYP00000006021 | ENSPPYP00000009604 | SMAD1 isoform 8. | E3 ubiquitin-protein ligase. | 0.914 |
| CR201_G0000132 | STUB1 | ENSPPYP00000006021 | ENSPPYP00000007837 | SMAD1 isoform 8. | STIP1 homology and U-box containing protein 1. | 0.658 |
| ENSPPYP00000016868 | BMPR1B | ENSPPYP00000016868 | ENSPPYP00000016680 | annotation not available | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.836 |
