ENSPPYP00000017056 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSA1	ENSPPYP00000005659	ENSPPYP00000006854	ENSPPYP00000005659	AHSA1 isoform 1.	annotation not available	0.697
AHSA1	ENSPPYP00000017056	ENSPPYP00000006854	ENSPPYP00000017056	AHSA1 isoform 1.	annotation not available	0.878
AHSA1	FKBP4	ENSPPYP00000006854	ENSPPYP00000004732	AHSA1 isoform 1.	Peptidylprolyl isomerase.	0.892
AHSA1	FKBP5	ENSPPYP00000006854	ENSPPYP00000018489	AHSA1 isoform 1.	Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (By similarity).	0.640
AHSA1	HSPA4	ENSPPYP00000006854	ENSPPYP00000017643	AHSA1 isoform 1.	Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.	0.638
AHSA1	HSPA8	ENSPPYP00000006854	ENSPPYP00000004564	AHSA1 isoform 1.	Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]	0.697
AHSA1	PTGES3	ENSPPYP00000006854	ENSPPYP00000005319	AHSA1 isoform 1.	Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.	0.865
AHSA1	STIP1	ENSPPYP00000006854	ENSPPYP00000003602	AHSA1 isoform 1.	STIP1 isoform 2.	0.973
AHSA1	SUGT1	ENSPPYP00000006854	ENSPPYP00000006144	AHSA1 isoform 1.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.410
ENSPPYP00000005659	AHSA1	ENSPPYP00000005659	ENSPPYP00000006854	annotation not available	AHSA1 isoform 1.	0.697
ENSPPYP00000005659	ENSPPYP00000017056	ENSPPYP00000005659	ENSPPYP00000017056	annotation not available	annotation not available	0.904
ENSPPYP00000005659	FKBP4	ENSPPYP00000005659	ENSPPYP00000004732	annotation not available	Peptidylprolyl isomerase.	0.522
ENSPPYP00000005659	FKBP5	ENSPPYP00000005659	ENSPPYP00000018489	annotation not available	Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (By similarity).	0.424
ENSPPYP00000005659	HSF1	ENSPPYP00000005659	ENSPPYP00000021274	annotation not available	HSF1 isoform 2.	0.875
ENSPPYP00000005659	HSPA4	ENSPPYP00000005659	ENSPPYP00000017643	annotation not available	Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family.	0.942
ENSPPYP00000005659	PTGES3	ENSPPYP00000005659	ENSPPYP00000005319	annotation not available	Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.	0.584
ENSPPYP00000005659	STIP1	ENSPPYP00000005659	ENSPPYP00000003602	annotation not available	STIP1 isoform 2.	0.912
ENSPPYP00000017056	AHSA1	ENSPPYP00000017056	ENSPPYP00000006854	annotation not available	AHSA1 isoform 1.	0.878
ENSPPYP00000017056	ENSPPYP00000005659	ENSPPYP00000017056	ENSPPYP00000005659	annotation not available	annotation not available	0.904
ENSPPYP00000017056	FKBP4	ENSPPYP00000017056	ENSPPYP00000004732	annotation not available	Peptidylprolyl isomerase.	0.885