UBE2QL1 protein (Pongo abelii) - STRING interaction network

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000012086	TMEM189-UBE2V1	ENSPPYP00000012086	ENSPPYP00000012429	annotation not available	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	0.981
ENSPPYP00000012086	UBA1	ENSPPYP00000012086	ENSPPYP00000022706	annotation not available	UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family.	0.681
ENSPPYP00000012086	UBA3	ENSPPYP00000012086	ENSPPYP00000015351	annotation not available	NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down- regulates steroid receptor activity. Necessary for cell cycle progression (By similarity).	0.793
ENSPPYP00000012086	UBA5	ENSPPYP00000012086	ENSPPYP00000015785	annotation not available	Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates UFM1 and SUMO2.	0.731
ENSPPYP00000012086	UBA6	ENSPPYP00000012086	ENSPPYP00000016457	annotation not available	UBA6 isoform 1.	0.681
ENSPPYP00000012086	UBA7	ENSPPYP00000012086	ENSPPYP00000015508	annotation not available	UBA7 isoform 1; Belongs to the ubiquitin-activating E1 family.	0.681
ENSPPYP00000012086	UBE2H	ENSPPYP00000012086	ENSPPYP00000020192	annotation not available	Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.	0.824
ENSPPYP00000012086	UBE2J2	ENSPPYP00000012086	ENSPPYP00000002333	annotation not available	Ubiquitin conjugating enzyme E2 J2.	0.778
ENSPPYP00000012086	UBE2Q1	ENSPPYP00000012086	ENSPPYP00000000906	annotation not available	Ubiquitin conjugating enzyme E2 Q1.	0.473
ENSPPYP00000012086	UBE2QL1	ENSPPYP00000012086	ENSPPYP00000017126	annotation not available	UBE2QL1 isoform 1.	0.455
TMEM189-UBE2V1	ENSPPYP00000012086	ENSPPYP00000012429	ENSPPYP00000012086	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	annotation not available	0.981
TMEM189-UBE2V1	UBA1	ENSPPYP00000012429	ENSPPYP00000022706	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family.	0.681
TMEM189-UBE2V1	UBA3	ENSPPYP00000012429	ENSPPYP00000015351	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	NEDD8-activating enzyme E1 catalytic subunit; Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down- regulates steroid receptor activity. Necessary for cell cycle progression (By similarity).	0.793
TMEM189-UBE2V1	UBA5	ENSPPYP00000012429	ENSPPYP00000015785	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates UFM1 and SUMO2.	0.731
TMEM189-UBE2V1	UBA6	ENSPPYP00000012429	ENSPPYP00000016457	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	UBA6 isoform 1.	0.681
TMEM189-UBE2V1	UBA7	ENSPPYP00000012429	ENSPPYP00000015508	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	UBA7 isoform 1; Belongs to the ubiquitin-activating E1 family.	0.681
TMEM189-UBE2V1	UBE2H	ENSPPYP00000012429	ENSPPYP00000020192	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.	0.824
TMEM189-UBE2V1	UBE2J2	ENSPPYP00000012429	ENSPPYP00000002333	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 J2.	0.776
TMEM189-UBE2V1	UBE2Q1	ENSPPYP00000012429	ENSPPYP00000000906	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 Q1.	0.455
TMEM189-UBE2V1	UBE2QL1	ENSPPYP00000012429	ENSPPYP00000017126	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	UBE2QL1 isoform 1.	0.455