UBE2QL1 protein (Pongo abelii) - STRING interaction network

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Score

UBE2QL1

UBE2QL1 isoform 1. (161 aa)

Predicted Functional Partners:

UBE2Q1

0.902

ENSPPYP00000012086

0.612

TMEM189-UBE2V1

0.612

UBE2H

0.541

UBE2J2

0.537

UBE2K

0.519

UBE2G2

0.502

UBE2J1

0.496

UBE2S

0.495

UBE2O

0.479

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000012086	TMEM189-UBE2V1	ENSPPYP00000012086	ENSPPYP00000012429	annotation not available	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	0.841
ENSPPYP00000012086	UBE2G2	ENSPPYP00000012086	ENSPPYP00000012839	annotation not available	Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).	0.934
ENSPPYP00000012086	UBE2H	ENSPPYP00000012086	ENSPPYP00000020192	annotation not available	Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.	0.934
ENSPPYP00000012086	UBE2J1	ENSPPYP00000012086	ENSPPYP00000018852	annotation not available	Ubiquitin conjugating enzyme E2 J1.	0.968
ENSPPYP00000012086	UBE2J2	ENSPPYP00000012086	ENSPPYP00000002333	annotation not available	Ubiquitin conjugating enzyme E2 J2.	0.937
ENSPPYP00000012086	UBE2K	ENSPPYP00000012086	ENSPPYP00000016399	annotation not available	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.973
ENSPPYP00000012086	UBE2O	ENSPPYP00000012086	ENSPPYP00000009725	annotation not available	Ubiquitin conjugating enzyme E2 O.	0.932
ENSPPYP00000012086	UBE2Q1	ENSPPYP00000012086	ENSPPYP00000000906	annotation not available	Ubiquitin conjugating enzyme E2 Q1.	0.612
ENSPPYP00000012086	UBE2QL1	ENSPPYP00000012086	ENSPPYP00000017126	annotation not available	UBE2QL1 isoform 1.	0.612
ENSPPYP00000012086	UBE2S	ENSPPYP00000012086	ENSPPYP00000011677	annotation not available	UBE2S isoform 1; Belongs to the ubiquitin-conjugating enzyme family.	0.972
TMEM189-UBE2V1	ENSPPYP00000012086	ENSPPYP00000012429	ENSPPYP00000012086	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	annotation not available	0.841
TMEM189-UBE2V1	UBE2G2	ENSPPYP00000012429	ENSPPYP00000012839	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).	0.934
TMEM189-UBE2V1	UBE2H	ENSPPYP00000012429	ENSPPYP00000020192	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.	0.934
TMEM189-UBE2V1	UBE2J1	ENSPPYP00000012429	ENSPPYP00000018852	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 J1.	0.968
TMEM189-UBE2V1	UBE2J2	ENSPPYP00000012429	ENSPPYP00000002333	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 J2.	0.937
TMEM189-UBE2V1	UBE2K	ENSPPYP00000012429	ENSPPYP00000016399	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.973
TMEM189-UBE2V1	UBE2O	ENSPPYP00000012429	ENSPPYP00000009725	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 O.	0.932
TMEM189-UBE2V1	UBE2Q1	ENSPPYP00000012429	ENSPPYP00000000906	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	Ubiquitin conjugating enzyme E2 Q1.	0.612
TMEM189-UBE2V1	UBE2QL1	ENSPPYP00000012429	ENSPPYP00000017126	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	UBE2QL1 isoform 1.	0.612
TMEM189-UBE2V1	UBE2S	ENSPPYP00000012429	ENSPPYP00000011677	Ubiquitin-conjugating enzyme E2 variant 1; Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF- kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repa [...]	UBE2S isoform 1; Belongs to the ubiquitin-conjugating enzyme family.	0.972