STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1013 aa)    
Predicted Functional Partners:
GNAS
GNAS isoform 2.
   
 0.756
ADCY5
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
  
 
0.736
GNAL
GNAL isoform 3.
   
 0.720
ADCY6
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
  
 
0.679
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
      
 0.600
DGKA
Diacylglycerol kinase.
   
  
 0.599
TENT4A
PAPD7 isoform 2.
      
 0.594
NPPC
Natriuretic peptide C.
    
 0.578
NKD1
NKD inhibitor of WNT signaling pathway 1.
      
 0.552
NSUN2
NSUN2 isoform 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.536
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.