| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT1 | DEPTOR | ENSPPYP00000007036 | ENSPPYP00000021144 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | DEPTOR isoform 1. | 0.653 |
| AKT1 | ENSPPYP00000009928 | ENSPPYP00000007036 | ENSPPYP00000009928 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | annotation not available | 0.861 |
| AKT1 | MAPKAP1 | ENSPPYP00000007036 | ENSPPYP00000021975 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | 0.962 |
| AKT1 | MLST8 | ENSPPYP00000007036 | ENSPPYP00000007913 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | MTOR associated protein, LST8 homolog. | 0.826 |
| AKT1 | RICTOR | ENSPPYP00000007036 | ENSPPYP00000017219 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | RICTOR isoform 1. | 0.973 |
| AKT1 | RPS6KB1 | ENSPPYP00000007036 | ENSPPYP00000009887 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | T0040019 isoform 1. | 0.985 |
| AKT1 | RPTOR | ENSPPYP00000007036 | ENSPPYP00000024617 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | RPTOR isoform 4. | 0.981 |
| DEPTOR | AKT1 | ENSPPYP00000021144 | ENSPPYP00000007036 | DEPTOR isoform 1. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.653 |
| DEPTOR | ENSPPYP00000009928 | ENSPPYP00000021144 | ENSPPYP00000009928 | DEPTOR isoform 1. | annotation not available | 0.574 |
| DEPTOR | MAPKAP1 | ENSPPYP00000021144 | ENSPPYP00000021975 | DEPTOR isoform 1. | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | 0.812 |
| DEPTOR | MLST8 | ENSPPYP00000021144 | ENSPPYP00000007913 | DEPTOR isoform 1. | MTOR associated protein, LST8 homolog. | 0.983 |
| DEPTOR | RICTOR | ENSPPYP00000021144 | ENSPPYP00000017219 | DEPTOR isoform 1. | RICTOR isoform 1. | 0.930 |
| DEPTOR | RPS6KB1 | ENSPPYP00000021144 | ENSPPYP00000009887 | DEPTOR isoform 1. | T0040019 isoform 1. | 0.955 |
| DEPTOR | RPTOR | ENSPPYP00000021144 | ENSPPYP00000024617 | DEPTOR isoform 1. | RPTOR isoform 4. | 0.980 |
| DEPTOR | TTI1 | ENSPPYP00000021144 | ENSPPYP00000012276 | DEPTOR isoform 1. | TELO2 interacting protein 1. | 0.781 |
| ENSPPYP00000009928 | AKT1 | ENSPPYP00000009928 | ENSPPYP00000007036 | annotation not available | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.861 |
| ENSPPYP00000009928 | DEPTOR | ENSPPYP00000009928 | ENSPPYP00000021144 | annotation not available | DEPTOR isoform 1. | 0.574 |
| ENSPPYP00000009928 | MAPKAP1 | ENSPPYP00000009928 | ENSPPYP00000021975 | annotation not available | Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...] | 0.724 |
| ENSPPYP00000009928 | MLST8 | ENSPPYP00000009928 | ENSPPYP00000007913 | annotation not available | MTOR associated protein, LST8 homolog. | 0.737 |
| ENSPPYP00000009928 | RICTOR | ENSPPYP00000009928 | ENSPPYP00000017219 | annotation not available | RICTOR isoform 1. | 0.853 |
