| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0037390 | EGFR | ENSPPYP00000010903 | ENSPPYP00000019671 | PIK3R2 isoform 1. | Receptor protein-tyrosine kinase. | 0.994 |
| CR201_G0037390 | ERBB2 | ENSPPYP00000010903 | ENSPPYP00000009527 | PIK3R2 isoform 1. | Receptor protein-tyrosine kinase. | 0.989 |
| CR201_G0037390 | GAB1 | ENSPPYP00000010903 | ENSPPYP00000016856 | PIK3R2 isoform 1. | GAB1 isoform 1. | 0.980 |
| CR201_G0037390 | PIK3CA | ENSPPYP00000010903 | ENSPPYP00000023529 | PIK3R2 isoform 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.999 |
| CR201_G0037390 | PIK3CB | ENSPPYP00000010903 | ENSPPYP00000015827 | PIK3R2 isoform 1. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.999 |
| CR201_G0037390 | PIK3CD | ENSPPYP00000010903 | ENSPPYP00000002213 | PIK3R2 isoform 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.997 |
| CR201_G0037390 | PIK3R1 | ENSPPYP00000010903 | ENSPPYP00000017341 | PIK3R2 isoform 1. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.997 |
| CR201_G0037390 | PIK3R3 | ENSPPYP00000010903 | ENSPPYP00000001627 | PIK3R2 isoform 1. | T0148502 isoform 1. | 0.996 |
| CR201_G0037390 | PTPN11 | ENSPPYP00000010903 | ENSPPYP00000005677 | PIK3R2 isoform 1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.979 |
| CR201_G0037390 | SRC | ENSPPYP00000010903 | ENSPPYP00000012270 | PIK3R2 isoform 1. | Tyrosine-protein kinase. | 0.961 |
| EGFR | CR201_G0037390 | ENSPPYP00000019671 | ENSPPYP00000010903 | Receptor protein-tyrosine kinase. | PIK3R2 isoform 1. | 0.994 |
| EGFR | ERBB2 | ENSPPYP00000019671 | ENSPPYP00000009527 | Receptor protein-tyrosine kinase. | Receptor protein-tyrosine kinase. | 0.996 |
| EGFR | GAB1 | ENSPPYP00000019671 | ENSPPYP00000016856 | Receptor protein-tyrosine kinase. | GAB1 isoform 1. | 0.996 |
| EGFR | PIK3CA | ENSPPYP00000019671 | ENSPPYP00000023529 | Receptor protein-tyrosine kinase. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.997 |
| EGFR | PIK3CB | ENSPPYP00000019671 | ENSPPYP00000015827 | Receptor protein-tyrosine kinase. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.994 |
| EGFR | PIK3CD | ENSPPYP00000019671 | ENSPPYP00000002213 | Receptor protein-tyrosine kinase. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.978 |
| EGFR | PIK3R1 | ENSPPYP00000019671 | ENSPPYP00000017341 | Receptor protein-tyrosine kinase. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.997 |
| EGFR | PIK3R3 | ENSPPYP00000019671 | ENSPPYP00000001627 | Receptor protein-tyrosine kinase. | T0148502 isoform 1. | 0.994 |
| EGFR | PTPN11 | ENSPPYP00000019671 | ENSPPYP00000005677 | Receptor protein-tyrosine kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.997 |
| EGFR | SRC | ENSPPYP00000019671 | ENSPPYP00000012270 | Receptor protein-tyrosine kinase. | Tyrosine-protein kinase. | 0.997 |
