| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCNH | CDK7 | ENSPPYP00000017463 | ENSPPYP00000017348 | CCNH isoform 4; Belongs to the cyclin family. | CDK7 isoform 1; Belongs to the protein kinase superfamily. | 0.999 |
| CCNH | ERCC2 | ENSPPYP00000017463 | ENSPPYP00000011316 | CCNH isoform 4; Belongs to the cyclin family. | ERCC2 isoform 1. | 0.991 |
| CCNH | ERCC3 | ENSPPYP00000017463 | ENSPPYP00000014246 | CCNH isoform 4; Belongs to the cyclin family. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | 0.991 |
| CCNH | GTF2E2 | ENSPPYP00000017463 | ENSPPYP00000020724 | CCNH isoform 4; Belongs to the cyclin family. | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. | 0.936 |
| CCNH | GTF2H1 | ENSPPYP00000017463 | ENSPPYP00000003947 | CCNH isoform 4; Belongs to the cyclin family. | General transcription factor IIH subunit 1. | 0.949 |
| CCNH | GTF2H3 | ENSPPYP00000017463 | ENSPPYP00000005801 | CCNH isoform 4; Belongs to the cyclin family. | GTF2H3 isoform 1. | 0.968 |
| CCNH | GTF2H4 | ENSPPYP00000017463 | ENSPPYP00000018363 | CCNH isoform 4; Belongs to the cyclin family. | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. | 0.988 |
| CCNH | GTF2H5 | ENSPPYP00000017463 | ENSPPYP00000019185 | CCNH isoform 4; Belongs to the cyclin family. | General transcription factor IIH subunit 5. | 0.949 |
| CCNH | LOC100456237 | ENSPPYP00000017463 | ENSPPYP00000017358 | CCNH isoform 4; Belongs to the cyclin family. | General transcription factor IIH subunit. | 0.973 |
| CCNH | MNAT1 | ENSPPYP00000017463 | ENSPPYP00000006678 | CCNH isoform 4; Belongs to the cyclin family. | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. | 0.998 |
| CDK7 | CCNH | ENSPPYP00000017348 | ENSPPYP00000017463 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | CCNH isoform 4; Belongs to the cyclin family. | 0.999 |
| CDK7 | ERCC2 | ENSPPYP00000017348 | ENSPPYP00000011316 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | ERCC2 isoform 1. | 0.988 |
| CDK7 | ERCC3 | ENSPPYP00000017348 | ENSPPYP00000014246 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required fo [...] | 0.990 |
| CDK7 | GTF2E2 | ENSPPYP00000017348 | ENSPPYP00000020724 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. | 0.818 |
| CDK7 | GTF2H1 | ENSPPYP00000017348 | ENSPPYP00000003947 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | General transcription factor IIH subunit 1. | 0.938 |
| CDK7 | GTF2H3 | ENSPPYP00000017348 | ENSPPYP00000005801 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | GTF2H3 isoform 1. | 0.989 |
| CDK7 | GTF2H4 | ENSPPYP00000017348 | ENSPPYP00000018363 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. | 0.982 |
| CDK7 | GTF2H5 | ENSPPYP00000017348 | ENSPPYP00000019185 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | General transcription factor IIH subunit 5. | 0.977 |
| CDK7 | LOC100456237 | ENSPPYP00000017348 | ENSPPYP00000017358 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | General transcription factor IIH subunit. | 0.971 |
| CDK7 | MNAT1 | ENSPPYP00000017348 | ENSPPYP00000006678 | CDK7 isoform 1; Belongs to the protein kinase superfamily. | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. | 0.997 |
