| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDNF | CR201_G0023793 | ENSPPYP00000003904 | ENSPPYP00000009322 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | 0.421 |
| BDNF | CRH | ENSPPYP00000003904 | ENSPPYP00000020903 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | CRH isoform 1. | 0.530 |
| BDNF | CRHBP | ENSPPYP00000003904 | ENSPPYP00000017409 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. | 0.503 |
| BDNF | CRHR2 | ENSPPYP00000003904 | ENSPPYP00000019809 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.539 |
| BDNF | HMGCR | ENSPPYP00000003904 | ENSPPYP00000017394 | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | 0.409 |
| CHGB | CRHBP | ENSPPYP00000011951 | ENSPPYP00000017409 | CHGB isoform 1. | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. | 0.486 |
| CHGB | HMGCR | ENSPPYP00000011951 | ENSPPYP00000017394 | CHGB isoform 1. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. | 0.487 |
| CR201_G0023793 | BDNF | ENSPPYP00000009322 | ENSPPYP00000003904 | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.421 |
| CR201_G0023793 | CRH | ENSPPYP00000009322 | ENSPPYP00000020903 | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | CRH isoform 1. | 0.998 |
| CR201_G0023793 | CRHBP | ENSPPYP00000009322 | ENSPPYP00000017409 | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. | 0.642 |
| CR201_G0023793 | CRHR2 | ENSPPYP00000009322 | ENSPPYP00000019809 | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.954 |
| CR201_G0023793 | UCN | ENSPPYP00000009322 | ENSPPYP00000014020 | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | UCN isoform 1. | 0.996 |
| CRH | BDNF | ENSPPYP00000020903 | ENSPPYP00000003904 | CRH isoform 1. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.530 |
| CRH | CR201_G0023793 | ENSPPYP00000020903 | ENSPPYP00000009322 | CRH isoform 1. | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | 0.998 |
| CRH | CRHBP | ENSPPYP00000020903 | ENSPPYP00000017409 | CRH isoform 1. | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. | 0.984 |
| CRH | CRHR2 | ENSPPYP00000020903 | ENSPPYP00000019809 | CRH isoform 1. | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.998 |
| CRH | UCN | ENSPPYP00000020903 | ENSPPYP00000014020 | CRH isoform 1. | UCN isoform 1. | 0.981 |
| CRHBP | BDNF | ENSPPYP00000017409 | ENSPPYP00000003904 | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. | 0.503 |
| CRHBP | CHGB | ENSPPYP00000017409 | ENSPPYP00000011951 | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. | CHGB isoform 1. | 0.486 |
| CRHBP | CR201_G0023793 | ENSPPYP00000017409 | ENSPPYP00000009322 | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. | CRHR1 isoform 5; Belongs to the G-protein coupled receptor 2 family. | 0.642 |
