| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0001249 | GLRX | ENSPPYP00000005584 | ENSPPYP00000017490 | TXNRD1 isoform 17. | GLRX isoform 1. | 0.788 |
| CR201_G0001249 | TXNDC8 | ENSPPYP00000005584 | ENSPPYP00000021835 | TXNRD1 isoform 17. | TXNDC8 isoform 3. | 0.683 |
| GLRX | CR201_G0001249 | ENSPPYP00000017490 | ENSPPYP00000005584 | GLRX isoform 1. | TXNRD1 isoform 17. | 0.788 |
| GLRX | GSR | ENSPPYP00000017490 | ENSPPYP00000020725 | GLRX isoform 1. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.801 |
| GLRX | RRM1 | ENSPPYP00000017490 | ENSPPYP00000004146 | GLRX isoform 1. | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.956 |
| GLRX | RRM2 | ENSPPYP00000017490 | ENSPPYP00000014130 | GLRX isoform 1. | Ribonucleotide reductase regulatory subunit M2. | 0.795 |
| GLRX | RRM2B | ENSPPYP00000017490 | ENSPPYP00000021083 | GLRX isoform 1. | Ribonucleoside-diphosphate reductase subunit M2 B; Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage (By similarity). Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.795 |
| GLRX | SULT1C2 | ENSPPYP00000017490 | ENSPPYP00000024237 | GLRX isoform 1. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.766 |
| GLRX | TXNDC8 | ENSPPYP00000017490 | ENSPPYP00000021835 | GLRX isoform 1. | TXNDC8 isoform 3. | 0.692 |
| GLRX | TXNRD2 | ENSPPYP00000017490 | ENSPPYP00000012925 | GLRX isoform 1. | Thioredoxin reductase 2. | 0.669 |
| GLRX | TXNRD3 | ENSPPYP00000017490 | ENSPPYP00000015043 | GLRX isoform 1. | TXNRD3 isoform 1. | 0.664 |
| GLRX | VNN2 | ENSPPYP00000017490 | ENSPPYP00000019056 | GLRX isoform 1. | VNN2 isoform 1. | 0.798 |
| GSR | GLRX | ENSPPYP00000020725 | ENSPPYP00000017490 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | GLRX isoform 1. | 0.801 |
| GSR | TXNDC8 | ENSPPYP00000020725 | ENSPPYP00000021835 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | TXNDC8 isoform 3. | 0.702 |
| RRM1 | GLRX | ENSPPYP00000004146 | ENSPPYP00000017490 | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | GLRX isoform 1. | 0.956 |
| RRM1 | RRM2 | ENSPPYP00000004146 | ENSPPYP00000014130 | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | Ribonucleotide reductase regulatory subunit M2. | 0.999 |
| RRM1 | RRM2B | ENSPPYP00000004146 | ENSPPYP00000021083 | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | Ribonucleoside-diphosphate reductase subunit M2 B; Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage (By similarity). Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
| RRM1 | TXNDC8 | ENSPPYP00000004146 | ENSPPYP00000021835 | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | TXNDC8 isoform 3. | 0.540 |
| RRM2 | GLRX | ENSPPYP00000014130 | ENSPPYP00000017490 | Ribonucleotide reductase regulatory subunit M2. | GLRX isoform 1. | 0.795 |
| RRM2 | RRM1 | ENSPPYP00000014130 | ENSPPYP00000004146 | Ribonucleotide reductase regulatory subunit M2. | Ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.999 |
